Recombinant Bovine Contactin-1 (CNTN1), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

CNTN1

Purity

>85% (SDS-PAGE)

Target Names

CNTN1

Uniprot NO.

Q28106

Alternative Names

CNTN1Contactin-1; Neural cell surface protein F3

Species

Bos taurus (Bovine)

Source

Yeast

Expression Region

21-999

Target Protein Sequence

EFTWHRRYGH GVSEEDKGFG PIFEEQPINT IYPEESPEGK VSLNCRARAS PFPVYKWRMN NGDIDLTSDR YSMVGGNLVI NNPDKQKDAG IYYCLASNNY GMVRSTEATL SFGYLDPFPP EERPEVRVKE GKGMVLLCDP PYHFPDDLSY RWLLNEFPVF ITMDKRRFVS QTNGNLYIAN VEASDKGNYS CFVSSPSITK SVFSKFIPLI PLPERTTKPY PADIVVQFKD VYALMGQNVT LECFALGNPV PDIRWRKVLE PMPSTAEIST SGAVLKIFNI QLEDEGIYEC EAENNRGKDK HQARIYVQAF PEWVEHINDT EVDIGSDLYW PCVATGKPIP TIRWLKNGYS YHRGELRLYD VTFENAGMYQ CIAENTHGAI YANAELKILA LAPTFEMNPM KKKILAAKGG RVIIECKPKA APKPTFLWSK GTERLVNSSR ILIWEDGSLE INNITRSDGG VYTCFVENNK GKANSTGTLV ITDPTRIILA PINADITVGE NATMQCAASF DPALDLTFVW SFNGYVIDFN KENIHYQRNF MLDSNGELLI RNAQLKHAGR YTCTAQTIVD NSSASADLVV RGPPGPPGGL RIEDIRATSV ALTWSRGSDN HSPISKYTIQ TKTILSDDWK DAKTDPPIIE GNMEAARAVD LIPWMEYEFR VVATNTLGIG EPSIPSNKIK TDGAAPNVAP SDVGGGGGSN RELTITWAPL SREYHYFNNF GYIVAFKPFD GEEWKKVTVT NPDTGRYVHK DETMRPSTAF QVKVKAFNNK GDGPYSLTAV IHSAQDAPSE APTAVGVKVL SSSEISVHWE HVVEKIVESY QIRYWASHDK EAAAHRVQVA SQEYSARLEN LLPDTQYFVE VRACNSAGCG PPSDMTETFT KKAPPSQPPR IISSVRSGSR YIITWDHVVA LSNESTVTGY KVLYRPDGQH DGKLYSTHKH SIEVPIPRDG EYVVEVRAHS DGGDGVVSQV KISGASILS
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Interaction with TNR induces a repulsion of neurons and an inhibition of neurite outgrowth.

Subcellular Location

Cell membrane; Lipid-anchor, GPI-anchor.

Protein Families

Immunoglobulin superfamily, Contactin family

Database Links

UNIGENE: Bt.349

KEGG: bta:281705

STRING: 9913.ENSBTAP00000042896

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