Recombinant Bovine Collagen alpha-2 (I) chain (COL1A2), partial

Product Details

Purity
>85% (SDS-PAGE)
Target Names
COL1A2
Uniprot NO.
Species
Bos taurus (Bovine)
Source
Yeast
Expression Region
80-1100
Target Protein Sequence
Q FDAKGGGPGP MGLMGPRGPP GASGAPGPQG FQGPPGEPGE PGQTGPAGAR GPPGPPGKAG EDGHPGKPGR PGERGVVGPQ GARGFPGTPG LPGFKGIRGH NGLDGLKGQP GAPGVKGEPG APGENGTPGQ TGARGLPGER GRVGAPGPAG ARGSDGSVGP VGPAGPIGSA GPPGFPGAPG PKGELGPVGN PGPAGPAGPR GEVGLPGLSG PVGPPGNPGA NGLPGAKGAA GLPGVAGAPG LPGPRGIPGP VGAAGATGAR GLVGEPGPAG SKGESGNKGE PGAVGQPGPP GPSGEEGKRG STGEIGPAGP PGPPGLRGNP GSRGLPGADG RAGVMGPAGS RGATGPAGVR GPNGDSGRPG EPGLMGPRGF PGSPGNIGPA GKEGPVGLPG IDGRPGPIGP AGARGEPGNI GFPGPKGPSG DPGKAGEKGH AGLAGARGAP GPDGNNGAQG PPGLQGVQGG KGEQGPAGPP GFQGLPGPAG TAGEAGKPGE RGIPGEFGLP GPAGARGERG PPGESGAAGP TGPIGSRGPS GPPGPDGNKG EPGVVGAPGT AGPSGPSGLP GERGAAGIPG GKGEKGETGL RGDIGSPGRD GARGAPGAIG APGPAGANGD RGEAGPAGPA GPAGPRGSPG ERGEVGPAGP NGFAGPAGAA GQPGAKGERG TKGPKGENGP VGPTGPVGAA GPSGPNGPPG PAGSRGDGGP PGATGFPGAA GRTGPPGPSG ISGPPGPPGP AGKEGLRGPR GDQGPVGRSG ETGASGPPGF VGEKGPSGEP GTAGPPGTPG PQGLLGAPGF LGLPGSRGER GLPGVAGSVG EPGPLGIAGP PGARGPPGNV GNPGVNGAPG EAGRDGNPGN DGPPGRDGQP GHKGERGYPG NAGPVGAAGA PGPQGPVGPV GKHGNRGEPG PAGAVGPAGA VGPRGPSGPQ GIRGDKGEPG DKGPRGLPGL KGHNGLQGLP GLAGHHGDQG APGAVGPAGP RGPAGPSGPA GKDGRIGQPG AVGPAGIRGS QGSQGPAGPP GPPGPPGPPG
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
Partial
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage
Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Type I collagen is a member of group I collagen (fibrillar forming collagen).
Gene References into Functions
  1. In advanced stage granulomas in Mycobacterium bovis-infected cattle, there was an increase in the expression of type I procollagen PMID:16154140
  2. Flow induced alpha2beta1 activation in cells on collagen, but not on fibronectin or fibrinogen. Conversely, alpha5beta1 and alphavbeta3 are activated on fibronectin and fibrinogen, but not collagen. PMID:16928957

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Subcellular Location
Secreted, extracellular space, extracellular matrix.
Protein Families
Fibrillar collagen family
Tissue Specificity
Forms the fibrils of tendon, ligaments and bones. In bones the fibrils are mineralized with calcium hydroxyapatite.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
No. 269, Shendun 5th Road, Donghu Hi-Tech Development Area, Hubei Province, 430206, P.R.China
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