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Recombinant Bovine Coagulation factor XI (F11), partial

Recombinant Bovine Coagulation factor XI (F11), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

F11

Purity

>85% (SDS-PAGE)

Target Names

F11

Uniprot NO.

Q5NTB3

Alternative Names

F11Coagulation factor XI; FXI; EC 3.4.21.27; Plasma thromboplastin antecedent; PTA) [Cleaved into: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain]

Species

Bos taurus (Bovine)

Source

Yeast

Expression Region

19-387

Target Protein Sequence

EC VTTLFQDACF KGGDITVAFA PNAKHCQIIC THHPRCLLFT FMTESSSEDP TKWYTCILKD SVTETLPMVN MTGAISGYSS KQCLHHISAC SKDMYVDLNM KGMNYNSSLA QSARECQQRC TDDTHCHFFT FATRHFPSIK DRNTCLLKNT QTGTPTSITK LHEVVSGFSL KSCGLSNLAC IRDIFPRTAF VDITIDTVMA PDPFVCRSIC THHPSCLFFT FLSEEWPTAS ERNLCLLKTS SSGLPSARFR KNRAFSGFSL QHCQHSVPVF CHSSFYRNTD FLGEELDIVD ADSHEACQKT CTNSIRCQFF TYSPSQESCN GGKGKCYLKL SANGSPTKIL HGTGSISGYT LRLCKMDNVC TTKIKTR
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Buffer

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

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Target Background

Function(From Uniprot)

Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX.

Gene References into Functions

Sequence analysis of the bovine coagulation factor XI (F11) gene revealed an unusually high number of non-synonymous mutations. However, none of the mutations in the F11 gene were concordant with Bovine neonatal pancytopenia status. PMID:21087874
DNA was extracted and amplified from the bovine mummified fetuses, and the samples were successfully tested for Factor XI gene deficiency in the mummies. PMID:15785014
Insertion of 15 nucleotides in the F11 gene is the causative mutation for factor XI deficiency in Japanese black cattle. PMID:16104386
The molecular basis of coagulopathy has been recognized in Holstein cattle as a 76-bp insertion in the coding region of the FXI gene PMID:19433912