Recombinant Bovine Alpha-S1-casein (CSN1S1)

Baculovirus
Mammalian cell

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

CSN1S1

Uniprot NO.

P02662

Species

Bos taurus (Bovine)

Source

Yeast

Expression Region

16-214

Target Protein Sequence

RPKHP IKHQGLPQEV LNENLLRFFV APFPEVFGKE KVNELSKDIG SESTEDQAME DIKQMEAESI SSSEEIVPNS VEQKHIQKED VPSERYLGYL EQLLRLKKYK VPQLEIVPNS AEERLHSMKE GIHAQQKEPM IGVNQELAYF YPELFRQFYQ LDAYPSGAWY YVPLGTQYTD APSFSDIPNP IGSENSEKTT MPLW
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Important role in the capacity of milk to transport calcium phosphate.; Antioxidant peptide has 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity.

Gene References into Functions

There were no associations between x genotype and fertility related traits in this study. PMID:27065254
The results give insight in phosphorylation of alpha(S1)-CN-8P and alpha(S1)-CN-9P, which seem to be regulated by a different set of genes. PMID:25200775
Report proteomic detection of bovine alpha-S1-casein in term and preterm human colostrum. PMID:23755758
Data indicate that the pepsin-pancreatin digest of alphaS-Casein exhibited anxiolytic-like activity. PMID:23580614
The genetic effects of thyroglobulin and casein alpha s1 alpha in the body fat distribution of cattle are reported. PMID:23148258
Alpha-S2-casein was less effective at preventing fibril formation by modified kappa-casein, whereas alpha- and alpha-S1 casein were comparably potent inhibitors. PMID:21457703
Single or multiple amino acid substitutions within IgE-binding epitopes result in reduced binding of milk-specific IgE antibodies. Critical amino acids should be evaluated with individual patient sera to determine B-cell-epitope heterogeneity. PMID:12897753
determination of T cell reactive epitopes PMID:15482858
EMSA analysis comparing allelic variants of a polymorphic AP-1 binding site in the promoter region of CSN1S1; specific and reduced protein binding of oligonucleotides containing the G variant of the CSN1S1-175bp binding site was shown PMID:15905454
An isoelectrofocusing pattern was identified, which may result from a novel CSN1S1 variant, named CSN1S1*I, migrating at an intermediate position between CSN1S1*B and CSN1S1*C. PMID:18096958
Substitution effects of paternal CSN2alpha (s1) allele versus CSN2 alpha(s2) allele on protein yield deviations (YDs) are significant, whereas their effects on milk and fat YDs are not. PMID:18263971