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Recombinant Bovine Aldehyde oxidase (AOX1), partial

Recombinant Bovine Aldehyde oxidase (AOX1), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

AOX1

Uniprot NO.

P48034

Alternative Names

AOX1; AOAldehyde oxidase 1; EC 1.2.3.1; Azaheterocycle hydroxylase 1; EC 1.17.3.-

Species

Bos taurus (Bovine)

Source

Yeast

Expression Region

1-1339

Target Protein Sequence

MEGGSELLFY VNGRKVTEKN VDPETMLLPY LRKKLRLTGT KYGCGGGGCG ACTVMISRYN PITKKIRHYP ANACLTPICS LYGAAVTTVE GIGSTKTRIH PVQERIAKCH GTQCGFCTPG MVMSLYTLLR NHPEPTLTQL NDALGGNLCR CTGYRPIINA CKTFCKTSGC CQSKENGVCC LDQGMNGLPE FEEGNETSLK LFSEEEFLPL DPTQELIFPP ELMTMAEKKT QKTRIFGSDR MTWISPVTLK ELLEAKVKYP QAPVVMGNTS VGPDMKFKGI FHPVIISPDR IEELSVVNYT DNGLTLGAAV SLAEVKDILA NVTRKLPEEK TQMYHALLKH LETLAGPQIR NMASLGGHIV SRHPDSDLNP LLAVGNCTLN LLSKEGRRQI PLNEQFLRKC PSADLKPEEI LISVNIPYSR KWEFVSAFRQ AQRQQNALAI VNSGMRVCFG KGDGIIRELS IAYGGVGPTT ILANNSCQKL IGRPWNEEML DAACRLILDE VSLPGSAPGG RVEFKRTLIV SFLFKFYLEV SQILKGMDLV HYPSLASKYE SALEDLHSRH YWSTLKYQNA DLKQLSQDPI GHPIMHLSGI KHATGEAIYC DDMPVVDREL FLTFVTSSRA HAKIVSIDVS AALSLPGVVD ILTGEHLPGI NTTFGFLTDA DQLLSTDEVS CVGQLVCAVI ADSEVQARRA AQQVKIVYQD LEPVILTIEE AIQNKSFFEP ERKLEYGNVD EAFKMVDQIL EGEIHMGGQE HFYMETQSML VVPKGEDREI DVYVSAQFPK YIQDITASVL KVSANKVMCH VKRVGGAFGG KVTKTGVLAA ITAFAANKHG RPVRCILERG EDILITGGRH PYLGKYKAGF MNDGRILALD MEHYNNAGAF LDESLFVIEM GLLKLENAYK FPNLRCRGWA CRTNLPSNTA LRGFGFPQAG LITEACITEV AAKCGLPPEK VRMINMYKEI DQTPYKQEIN TKNLTQCWKE CMATSSYTLR KAAVEKFNSE NYWKKKGLAM VPLKYPIGLG SVAAGQAAAL VHIYLDGSVL VTHGGIEMGQ GVHTKMIQVV SRELRMPLSS IHLRGTSTET IPNTNPSGGS VVADLNGLAV KDACQTLLKR LKPIISKNPK GTWKDWAQAA FNESISLSAT GYFRGYESNI NWETGEGHPF EYFVYGAACS EVEIDCLTGA HKNIRTDIVM DVGYSINPAL DVGQIEGAFI QGMGLYTIEE LNYSPQGVLY TRGPNQYKIP AICDIPMELH ISFLPPSENS NTLYSSKGLG ESGIFLGCSV FFAIHDAIRA ARQERGLPGP LRLNSPLTPE KIRMACEDKF TKMIPRDEPG SYVPWSVPI
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function(From Uniprot)

Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide, N-methylphthalazinium and phthalazine, as well as aldehydes, such as benzaldehyde, retinal, pyridoxal, and vanillin. Plays a key role in the metabolism of xenobiotics and drugs containing aromatic azaheterocyclic substituents. Is probably involved in the regulation of reactive oxygen species homeostasis. May be a prominent source of superoxide generation via the one-electron reduction of molecular oxygen. Also may catalyze nitric oxide (NO) production via the reduction of nitrite to NO with NADH or aldehyde as electron donor. May play a role in adipogenesis.

Subcellular Location

Cytoplasm.

Protein Families

Xanthine dehydrogenase family

Tissue Specificity

Expressed at high levels in liver, lung and spleen. Also expressed in kindey, eye, testis, duodenum, esophagus and thymus (at protein level).

Database Links

UNIGENE: Bt.45005

KEGG: bta:338074

STRING: 9913.ENSBTAP00000012827

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