Recombinant Bovine 72 kDa type IV collagenase (MMP2)

1. this study shows that differential FFAR1 signaling is associated with gene expression or gelatinase granule release in bovine neutrophils PMID:27363707
2. NADPH oxidase plays an important role in proMMP-2 expression and activation and MMP-2 mediated SMC proliferation occurs through the involvement of Spm-Cer-S1P signaling axis under ANG II stimulation of PASMCs PMID:27210740
3. The expression patterns of MMP1, MMP2, and MMP8 were explored during fetal and postnatal development of longissimus dorsi muscle in cattle, and the relationships of MMP1, MMP2, and MMP8 expression levels with meat quality traits were analyzed in cattle. The expression of MMP1, MMP2, and MMP8 were also tested in four kinds of fat tissues and three kinds of skeletal muscle tissues. PMID:26985938
4. The results showed that a decrease in MMP-1 and MMP-2 gene expression is accompanied with a decrease in NO concentrations in infertile cows affected with ovarian cysts. PMID:25496672
5. Activation of cytosolic MMP-9 and MMP-2 was investigated in the retinal endothelial cells incubated in high glucose for 6-96 h, and correlated with their mitochondrial accumulation and mitochondrial damage. PMID:23891690
6. Data indicate the involvement of PKC-alpha in proMMP-2 activation and inhibition of TIMP-2 expression by NF-kappaB-MT1-MMP-dependent and -independent pathway. PMID:23266860
7. Data suggest that EMMPRIN derived from endometrial epithelial cells regulates expression of matrix metalloproteinases (MMP-2; MMP-14) in endometrial stromal cells; expression of stromal MMPs is significantly higher in coculture with epithelial cells. PMID:23115270
8. Adding pure bovine MMP-2 to the smooth muscle membrane suspension causes an increase in Ca(2+)-ATPase activity, but the pretreatment with TIMP-2 inhibits the increase in the enzyme activity PMID:22905396
9. A differential pattern of matrix metalloproteinase-2 and Tissue inhibitor metalloproteinase-2 was observed in cow uteri with adenomyosis. PMID:21626345
10. MMP-14, MMP-2 and TIMP-2 are co-localized in the fetal compartment and therefore could influence the timely release of fetal membranes in cattle. PMID:21247626
11. Results describe distinct changes in expression of MMP2, MMP14, and the metallopeptidase inhibitor TIMP2 between different phases of the estrous cycle indicating an endocrine regulation. PMID:20887771
12. EMMPRIN from the luminal epithelium may regulate the expression of stromal MMP-2 and MMP-14 suggesting a role in adhesion and fusion of embryo to luminal epithelium. PMID:20540754
13. High shear stress up-regulates type IV collagen synthesis and down-regulates MMP-2 secretion in endothelial cells. PMID:20490867
14. increased MMP-2 activity subsequently played a pivotal role in stimulating Ca2+ ATPase activity in bovine pulmonary vascular smooth muscle plasma membrane PMID:12102173
15. MMP2 has a role in the oxidant activation of Ca2+Atpase PMID:12236590
16. results suggest a significant role of matrix metalloproteinase-2 and-9 in growth and development of bovine follicle PMID:12586316
17. Cells constitutively produced proMMP-9 and proMMP-2, and treatment with TNFalpha, hepatocyte growth factor, and 12-O-tetradecanoylphorbol 13-acetate resulted in significant increase in level of proMMP-9 but not in level of proMMP-2. PMID:12606436
18. MMP-2 and MMP-9 production in blastocysts attached to the endometrial cells is regulated by TNF-alpha and TNF-beta PMID:14967948
19. study suggests that MMP-2 plays an important role in regulating Ca2+ATPase activity, and ATP-dependent and Na+-dependent Ca2+ uptake in microsomes of bovine pulmonary artery smooth muscle during treatment with peroxynitrite PMID:15026147
20. reveal a potentially novel role for strain-induced endothelial matrix metalloproteinase-2 in regulating vascular smooth muscle cell migration PMID:15219830
21. Results describe the isolation of matrix metalloproteinase 2 (MMP-2) from the MMP-2/tissue inhibitor of metalloproteinase 2 (TIMP-2) complex, and the characterization of both isolated MMP-2 and the complex itself. PMID:15374620
22. MMP-2 is predominantly produced by large luteal cells and endothelial cells, and plays an essential role in luteal remodeling and angiogenesis. PMID:15570615
23. oxidants inactivate TIMP-2, and the resulting activation of MMP-2 subsequently inhibits Na+ dependent Ca2+ uptake in the microsomes PMID:15792356
24. Results suggest that MMP-2, MMP-9, and TIMP-2 mRNAs are expressed in bovine placentomes during the gestational and postpartum periods and that these enzymes, in conjunction with steroidogenic enzymes, mediate fetal membrane detachment after parturition. PMID:17154296
25. MMP2 is responsible for collagen denaturation in the last part of gradual cervical ripening. PMID:18361420
26. Relative expression of MMP-9 and MMP-2 increased in synovial fluid from calves with experimentally induced septic arthritis, with relative expression remaining high for several days after E. coli infection. PMID:18672966
27. MMP-2 gene expression declined with the progress of gestation, but its intensity was maintained at a high level during the peri-implantation period and increased in late gestation. PMID:19116037

Show More

Hide All

UNIGENE: Bt.5313

KEGG: bta:282872

STRING: 9913.ENSBTAP00000025657