Home
Product
Protein
Recombinant Proteins
Recombinant Bothrops jararacussu Venom nerve growth factor (NGF)

Recombinant Bothrops jararacussu Venom nerve growth factor (NGF)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
Have Questions?	Leave a Message or Start an on-line Chat

Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Abbreviation

NGF

Purity

>85% (SDS-PAGE)

Target Names

NGF

Uniprot NO.

Q90W38

Species

Bothrops jararacussu (Jararacussu)

Source

Yeast

Expression Region

123-241

Target Protein Sequence

EDHPVHNR GEYSVCDSVN VWVANKTTAT DIRGNVVTVM VDVNINNNVY KQYFFETKCR NPNPVPTGCR GIDARHWNSY CTTTNTFVKA LTMEGNQASW RFIRIDTACV CVISRKNENF G
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

■ Customer Reviews

Submit a Review here

Target Background

Function(From Uniprot)

Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons as well as basal forebrain cholinergic neurons in the brain. Its relevance in the snake venom is not clear. However, it has been shown to inhibit metalloproteinase-dependent proteolysis of platelet glycoprotein Ib alpha, suggesting a metalloproteinase inhibition to prevent metalloprotease autodigestion and/or protection against prey proteases. Binds a lipid between the two protein chains in the homodimer. The lipid-bound form promotes histamine relase from mouse mast cells, contrary to the lipid-free form.

Subcellular Location

Secreted.

Protein Families

NGF-beta family

Tissue Specificity

Expressed by the venom gland.

Promotions