Recombinant Bombyx mori Chromodomain-helicase-DNA-binding protein 1 (CHD1), partial

Product Details

Purity
>85% (SDS-PAGE)
Target Names
CHD1
Uniprot NO.
Alternative Names
CHD1Chromodomain-helicase-DNA-binding protein 1; CHD-1; EC 3.6.4.12; ATP-dependent helicase CHD1
Species
BOMMO(Silk moth)
Source
Yeast
Expression Region
1-1365
Target Protein Sequence
MRRGKKGVTG NVTTIYYIEE HGDPNEGCDP NDEDSTEPQY LIKWKGWSHI HNTWESEKTI NDQKVKGLKK LENFIKKEVE ISWWRQQAGP EDIDYYECQS ELQQELVKTY NNVERIIAEQ NRELEGGGTA HEYFCKWESL PYADATWEDA VLIEKRWPVE VEHFKSREAA KSTPSRHCPV LKRRPKFHQI KEQPEYVGKD SSYHLRDYQM DGLNWLIHSW CKDNSVILAD EMGLGKTIQT ICFLYYLFKS QHLYGPFLCV VPLSTMTAWQ REFQQWAPDI NVVTYIGDVS SRDIIRQFEW SFSSSKRLKF NAILTTYEIL LKDRQFLRSF SWACLLVDEA HRLKNDDSLL YKALKEFDTN HRLLVTGTPL QNSLKELWAL LHFIMPYKFE SWEDFEKDHE DAATKGYEKL HKQLEPFILR RQKKDVEKSL PAKVEQILRV EMTSIQKQYY KWILTKNYSA LRKGVKGSIN TFINIVIELK KCCNHALLTK PEDFESRASL ATSDAVEKLL RGSGKLLLLD KLLCRLKETG HRVLIFSQMV RMLDILAEYL QRRHFPFQRL DGSIKGELRK QALDHFNAEG SQDFCFLLST RAGGLGINLA TADTVIIFDS DWNPQNDLQA QARAHRIGQK NQVNIYRLVT ARSVEEDIVE RAKRKMVLDH LVIQRMDTTG KTVLNKRDAS GTTANNPFNK EDLNAILKFG AEELFKDDEE NDEDPVCDID EILQRAETRD EGPAMVGDEL LSAFKVASFT FDEEKAVNEL KKDNADEEPK DWDDIIPENV RKTIAEAEKL KEMEDIYLPP RRKNQLQNNA DGGRRRRGRS GDGGDGDGVD GDGEAESDAS DGEASADDDR PRKRGRPPAS HREKIKGFTD QEIRRFVKSY KKFSAPLKHL DSIACDAELQ EKPLAELKRL GEILQERCKA VLSETAEPSE QNEGRKNNRK TFKLGGVPVN AKTLAACQDE LAALDDFLPQ TKEERLKWQL DFRTRPANFD VEWNVSDDSK LLAGIYQYGL GSWEAIKMDS SFEIGDKILT NEDKKPQAKH LQSRAEYLLK LIKKLLDQKN GKQKMKKPRP KRANKEPVTK DIVEDDGSSA EDKKTKGVKN DKTEKGKLKI EEVSTHDETS NDKKEKDKKR KKDEDRKGDK SKGRKKPRQR GNEGIPGPMH FTANNEPRAL EVLGDLDPSV FEECKEKMRP VKKALKALDN PDQSLSETEQ VSRTRACLTQ IGTQIDLCVE AYPDSQKVEW RSNLWYFVSK FTNFDAKQLY KLYKYGLKKN EASKQKDGKH KENVKTNNRN NHNSINHLKS FKKNSNSKQK SDTNDKKEKK MKLEKEKTDK HDKNQHTSGV KRKLEDGECD PEPNDNKRHE RYVVD
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
Partial
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage Condition
Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)
ATP-dependent chromatin-remodeling factor which functions as substrate recognition component of the transcription regulatory histone acetylation (HAT) complex SAGA. Regulates polymerase II transcription. Also required for efficient transcription by RNA polymerase I, and more specifically the polymerase I transcription termination step. Regulates negatively DNA replication. Not only involved in transcription-related chromatin remodeling, but also required to maintain a specific chromatin configuration across the genome. Required for maintaining open chromatin and pluripotency in embryonic stem cells. Has a key role in chorion gene regulation and nucleosome positioning. Its binding to middle chorion gene promoters is correlated with H3K4 methylation and TFIID recruitment.
Gene References into Functions
  1. CHD1 is a critical factor for proper development of the follicular epithelium in terms of whole-cell chromatin arrangement. PMID:18817785

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Subcellular Location
Nucleus. Chromosome.
Protein Families
SNF2/RAD54 helicase family
Database Links
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No. 269, Shendun 5th Road, Donghu Hi-Tech Development Area, Hubei Province, 430206, P.R.China
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