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Recombinant Aspergillus oryzae Autophagy-related protein 13 (atg13), partial

Recombinant Aspergillus oryzae Autophagy-related protein 13 (atg13), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

atg13

Purity

>85% (SDS-PAGE)

Target Names

atg13

Uniprot NO.

Q2ULT1

Alternative Names

atg13; AO090003000280Autophagy-related protein 13

Species

Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)

Source

Yeast

Expression Region

1-974

Target Protein Sequence

MHQHPRSPAP TAPTSSARPN SSRSRELDYR PNSPAADVRV HNSRGLGIET EPDSSGQTVQ PAKEAIAKLN QIISNYHTKA ALIILHSRIE LPPSFNKGSD TPRVNRWFNV EIEDTDVLRE QLRTWRTCDA TENRPPPLII ETYLDTKGLT NNQTLVALDE NGKRWDVLEA LAASQQAHPV RPPSASSDDV ILERWRVELG DTSNALPADL GSILPTVYKK SIVLFRSLFT YSKFLPAWKF AKRNGRLRAN PALRIKYRII IGSPNQVSSK PDHLTMPLYE SSSKVVETYS FGVTDSPAGP FSAQVTYRTS CDFRVDDSEA LLSSRFMGAD DEIFRPSLPT RVVDSKVPPP EIGSLPQERR TIEDPDPGRA YGSLSTFHQV GPTTSASPIS ALRAKGKLGT SSPSSPGSSS RKALAVAKAS PVGRAAALAS EGSPGVVRRP SISFQPFKAP PLSASPSLVD PPLSSPRSVS GPRPHPPMAA SARKSFPAVQ DNSIASPSSA SPRPSSISRY SSAFSHRRGR PSSGGINKLE DDTSSGKASA TSSAQPGSGL LAEPTGTSAD SIHADDENIS EFLKMLDLRK DLLNTSGSAA LDATARRTTV TSAALTRFQR MRDSNAALSD SMSSSLLLQR SSNSSSKQLS GVPPMVAGTS ISTASSPGKP ISPHTPHTPA IPSRLSSNSI VDYTHSEGNG TELSQGHGSP LDENTSDGTT MEHGPSAVNA IDIPTSPRLF PPVYRRSSSA AHRPRTVAVD DDEIFPFNRS VSLGAEERSN LSLGALHRQH EYESSDTATH RAQREPRPMS SNEDAVVPPS SITRGQGSHK GVTPGPTVAS SSSSHHHVYQ PRFSHSRGRG SSGGHHSLSS GSSSLARGAA ITPGLAERES ERDGNGSGSN SVTSAMEDRR GVGRRPSAGR GGPPQSAQLE EDEPLLFAMS DFGASRRSFE EGKHVNHAHD PTGNIAGSRR GGSSRRGGGF HAWS
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Activates the atg1 kinase in a nutritional condition dependent manner through the TOR pathway, leading to autophagy. Also involved in cytoplasm to vacuole transport (Cvt) and more specifically in Cvt vesicle formation. Seems to play a role in the switching machinery regulating the conversion between the Cvt pathway and autophagy. Finally, atg13 is also required for glycogen storage during stationary phase.

Gene References into Functions

The DeltaAoatg13 mutant developed conidiophores and conidia, although the number of conidia was decreased compared with the wild-type strain, while conidiation in the DeltaAoatg4 and DeltaAoatg15 mutants was not detected. PMID:21204928

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Subcellular Location

Cytoplasm. Preautophagosomal structure.

Protein Families

ATG13 family, Fungi subfamily

Database Links

KEGG: aor:AO090003000280

STRING: 5062.CADAORAP00000918

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