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Recombinant Arabidopsis thaliana Telomerase reverse transcriptase (TERT), partial

Recombinant Arabidopsis thaliana Telomerase reverse transcriptase (TERT), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

TERT

Purity

>85% (SDS-PAGE)

Target Names

TERT

Uniprot NO.

Q9SPU7

Alternative Names

TERT; At5g16850; F5E19.190; Telomerase reverse transcriptase; AtTERT; EC 2.7.7.49

Species

Arabidopsis thaliana (Mouse-ear cress)

Source

Yeast

Expression Region

1-1123

Target Protein Sequence

MPRKPRHRVP EILWRLFGNR ARNLNDAIVD LIPNRNIQPE QCRCRGQGCL GCSSDKPAFL LRSDDPIHYR KLLHRCFVVL HEQTPPLLDF SPTSWWSQRE IVERIIEMMQ SGCDCQNVIC ARYDKYDQSS PILELLTSSS WEFLLKRVGH DVMVYLLQQT SIFLPLLGKK HQQVSGPPLC IKHKRTLSVH ENKRKRDDNV QPPTKRQWLS SAVDDCPKDD SATITPIVGE DVDQHREKKT TKRSRIYLKR RRKQRKVNFK KVDCNAPCIT PSTNGKVSTG NDEMNLHIGI NGSLTDFVKQ AKQVKRNKNF KFGLSETYSV IPPNHILKTL RPNCSDSKLL MNHIFGEVNV WSTTPSHGKG NCPSGSICLY HSLLKSLKNL IGKTKSSHLK MLLDKHCPVL LLQEDALKSG TTSQSSRRQK ADKLPHGSSS SQTGKPKCPS VEERKLYCTN DQVVSFIWAI CRYIVPESLL GTTHQMRVLR KNIAWFVSRR RNEKCTVNQF LHKVKPSDFP FFARKELCCM VNGHELQSES IRSTQQMLCT KWISWLFLEI VKKLVHFNFY ATESQGGRLN IYYYRKRSWE RLISKEISKA LDGYVLVDDA EAESSRKKLS KFRFLPKANG VRMVLDFSSS SRSQSLRDTH AVLKDIQLKE PDVLGSSVFD HDDFYRNLCP YLIHLRSQSG ELPPLYFVVA DVFKAFDSVD QGKLLHVIQS FLKDEYILNR CRLVCCGKRS NWVNKILVSS DKNSNFSRFT STVPYNALQS IVVDKGENHR VRKKDLMVWI GNMLKNNMLQ LDKSFYVQIA GIPQGHRLSS LLCCFYYGHL ERTLIYPFLE EASKDVSSKE CSREEELIIP TSYKLLRFID DYLFVSTSRD QASSFYHRLK HGFKDYNCFM NETKFCINFE DKEEHRCSSN RMFVGDNGVP FVRWTGLLIN SRTFEVQVDY TRYLSGHISS TFSVAWQNKP VRNLRQKLCY FLVPKCHPIL FDSNINSGEI VRLNIYQIFL LAAMKFHCYV YEVSRFWKLH PQTLFKFITI SVRYMFRLIN RRVRRINTGS SFRPVLKLYK EEVIWLGLDA YIQVLKKKNS RYRMLLIYLK SALSKHSLSQ QLSSELRYAT DRSNSSSLWK LNY
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Required to prevent genome instability induced by breakage-fusion-bridge (BFB) cycles. Can extend completely non-telomeric sequences using RNA template in vitro.

Gene References into Functions

Telomere shortening is more rapid in fas tert double mutants than in fas1, fas2 or tert single mutant plants. PMID:23564254
Silencing of the AtTERT gene is associated with increased H3K27me3 loading and maintenance of its euchromatic environment. PMID:22511802
AtTERT, the telomerase catalytic subunit, accumulates in the plant nucleolus, and AtNAP57 associates with active telomerase RNP particles in an RNA-dependent manner. PMID:18212040
Attert (-/-) mutant plants were propagated from seeds coming either from the lower-most or the upper-most siliques (L- and U-plants) and the length of their telomeres were followed over several generations. PMID:18239859