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Recombinant Arabidopsis thaliana Putative E3 ubiquitin-protein ligase RING1a (RING1A), partial

Recombinant Arabidopsis thaliana Putative E3 ubiquitin-protein ligase RING1a (RING1A), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Abbreviation

RING1A

Purity

>85% (SDS-PAGE)

Target Names

RING1A

Uniprot NO.

Q9FKW0

Alternative Names

RING1A; RF434; At5g44280; K9L2.3; Putative E3 ubiquitin-protein ligase RING1a; EC 2.3.2.27; Polycomb complex protein RING1a; Protein RING1a; AtRING1a; RING-type E3 ubiquitin transferase RING1a; Ring finger protein 434

Species

Arabidopsis thaliana (Mouse-ear cress)

Source

Yeast

Expression Region

1-522

Target Protein Sequence

MSVKNNSFSS AEIPDVADQP RDRFNPEATQ DLQEKDETKE EKEGDEEVKH DEAEEDQEVV KPNDAEEDDD GDDAEEDEEE EVEAEEDEEA EEEEEEEEEE EEEEEDSKER SPSSISGDQS EFMEIDLGEI RKDVQCPICL GIIKKTRTVM ECLHRFCREC IDKSMRLGNN ECPACRKHCA SRRSLRDDPK FDALIAALFT NIDSYEEEEL AFHEDEMARN KQIQASIAQI SQRQSEALVK RRSLGKEAAV LMRSPRIASG SRRRRNSRNM EQQNASEAHE DDDNDDNNNR GRDKDSSSDE RGTEVRQKKR RKRSTSRSTQ HPSSSGANKN NGNCADNDTE VYRDTKGISP GLVWNPEILA WGRGGTRSNT RHGNNTSGGS SKSVRNARVN KLVEYLRSSV DGSSVELDIH VKLVSLDTKC IPDLPQPYLC CRPTLLVKQL REFVALQIHL KTEEVELLVT RRRVGEDAAI ENLPAVTPAS AAASKDEMLS LEDNETLSRL KIDFISSHEQ HLIIAYRKKQ TE
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Putative E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-119' of histone H2A (H2AK119ub), thereby playing a central role in histone code and gene regulation.; As part of the PRC1-like complex, repress class I KNOX gene expression. PcG PRC1 complex maintains the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, rendering chromatin heritably changed in its expressibility.

Gene References into Functions

RING1A suppresses the expression of MAF4 and MAF5 through affecting H3K27me3 levels at these loci to regulate the floral transition PMID:24553292
AtRING1a is elevated in the Atbmi1a Atbmi1b mutant, suggesting a self-regulatory feedback mechanism. PMID:21060339

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Subcellular Location

Nucleus.

Database Links

UNIGENE: At.30083

KEGG: ath:AT5G44280

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