Recombinant Arabidopsis thaliana Protein BREAST CANCER SUSCEPTIBILITY 1 homolog (BRCA1), partial

Product Details

Abbreviation
BRCA1
Purity
>85% (SDS-PAGE)
Target Names
BRCA1
Uniprot NO.
Alternative Names
BRCA1; At4g21070; T13K14.230Protein BREAST CANCER SUSCEPTIBILITY 1 homolog; AtBRCA1
Species
Arabidopsis thaliana (Mouse-ear cress)
Source
Yeast
Expression Region
1-941
Target Protein Sequence
MADTSHLERM GRELKCPICL SLYNSAVSLS CNHVFCNACI VKSMKMDATC PVCKIPYHRR EIRGAPHMDS LVSIYKNMED ASGIKLFVSQ NNPSPSDKEK QVRDASVEKA SDKNRQGSRK GRASKRNEYG KTKEIDVDAP GPIVMKPSSQ TKKRVQLLQN LSAESLTKPT ESVETAEKPK DYTENTVIRL DEHPSLNKEG NLSPFFWLRD EDDGENSSQR TESDQLLGTT PVNVPSFSDL MDSDHESPSK EDEQQKPNPG DMFDSEMFEW TQRPCSPEIL PSPVKAKVLG RDEIDLTQKK LPKVKVASSK CKNRKAGSAR NTVARRSIGV SQEDNMESSA AATISEQQDS RGTSGTIIRN DVNTDENVKA KRATRSKAQS TRVQSDLNVS NEADGKQGTK RKRSSIKSSP AHPIAGPNEL SLGTEIVGKG DQDQAHGPSD THPEKRSPTE KPSLKKRGRK SNASSSLKDL SGKTQKKTSE KKLKLDSHMI SSKATQPHGN GILTAGLNQG GDKQDSRNNR KSTVGKDDHT MQVIEKCSTI NKSSSGGSAH LRRCNGSLTK KFTCAFCQCS EDTEASGEMT HYYRGEPVSA DFNGGSKVIH VHKNCAEWAP NVYFNDLTIV NLDVELTRSR RISCSCCGLK GAALGCYNKS CKNSFHVTCA KLIPECRWDN VKFVMLCPLD ASIKLPCEEA NSKDRKCKRT PKEPLHSQPK QVSGKANIRE LHIKQFHGFS KKLVLSCSGL TVEEKTVIAE FAELSGVTIS KNWDSTVTHV IASINENGAC KRTLKFMMAI LEGKWILTID WIKACMKNTK YVSEEPYEIT MDVHGIREGP YLGRQRALKK KPKLFTGLKF YIMGDFELAY KGYLQDLIVA AGGTILRRRP VSSDDNEAST IVVFSVEPSK KKTLTQRRSD AEALAKSARA RAASSSWVLD SIAGCQILVL I
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
Partial
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage Condition
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)
Plays a role in DNA repair and in cell-cycle control. Required for the repair of DNA double-strand breaks (DSBs), both natural and induced by genotoxic stress, by homologous recombination (HR).
Gene References into Functions
  1. A homologous recombination defect is apparent in Atbrca1 mutants. PMID:20817926

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Subcellular Location
Nucleus.
Tissue Specificity
Expressed ubiquitously with highest levels in flower buds. Mostly expressed in flowers and siliques, and, to a lower extent, in roots, rosette leaves, inflorescence and young cauline leaves.
Database Links

UNIGENE: At.32665

KEGG: ath:AT4G21070

STRING: 3702.AT4G21070.1

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