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Recombinant Arabidopsis thaliana Double-strand break repair protein MRE11 (MRE11), partial

Recombinant Arabidopsis thaliana Double-strand break repair protein MRE11 (MRE11), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

MRE11

Purity

>85% (SDS-PAGE)

Target Names

MRE11

Uniprot NO.

Q9XGM2

Alternative Names

MRE11; At5g54260; MDK4.8; Double-strand break repair protein MRE11; AtMre11

Species

Arabidopsis thaliana (Mouse-ear cress)

Source

Yeast

Expression Region

1-720

Target Protein Sequence

MSREDFSDTL RVLVATDCHL GYMEKDEIRR HDSFKAFEEI CSIAEEKQVD FLLLGGDLFH ENKPSRTTLV KAIEILRRHC LNDKPVQFQV VSDQTVNFQN AFGQVNYEDP HFNVGLPVFS IHGNHDDPAG VDNLSAIDIL SACNLVNYFG KMVLGGSGVG QITLYPILMK KGSTTVALYG LGNIRDERLN RMFQTPHAVQ WMRPEVQEGC DVSDWFNILV LHQNRVKSNP KNAISEHFLP RFLDFIVWGH EHECLIDPQE VSGMGFHITQ PGSSVATSLI DGESKPKHVL LLEIKGNQYR PTKIPLTSVR PFEYTEIVLK DESDIDPNDQ NSILEHLDKV VRNLIEKASK KAVNRSEIKL PLVRIKVDYS GFMTINPQRF GQKYVGKVAN PQDILIFSKA SKKGRSEANI DDSERLRPEE LNQQNIEALV AESNLKMEIL PVNDLDVALH NFVNKDDKLA FYSCVQYNLQ ETRGKLAKDS DAKKFEEDDL ILKVGECLEE RLKDRSTRPT GSSQFLSTGL TSENLTKGSS GIANASFSDD EDTTQMSGLA PPTRGRRGSS TANTTRGRAK APTRGRGRGK ASSAMKQTTL DSSLGFRQSQ RSASAAASAA FKSASTIGED DVDSPSSEEV EPEDFNKPDS SSEDDESTKG KGRKRPATTK RGRGRGSGTS KRGRKNESSS SLNRLLSSKD DDEDEDDEDR EKKLNKSQPR VTRNYGALRR
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.

Gene References into Functions

Functional and full-length AtMRE11 is essential for activation of the cell cycle arrest, transcriptional regulation and DNA repair upon induction of double strand break (DSB). PMID:27007017
TAF1 interaction with MRE11 is mediated by the C-terminal bromodomain of TAF1. PMID:26358508
functions of MRE11 in Arabidopsis meiosis PMID:24205310
The Atdfo Atmre11 double mutant had no such chromosome fragmentation, indicating that AtDFO is required for DNA double-strand break (DSB) formation. PMID:22694475
The cytological behavior of a possible early recombination nodules component, MRE11, a protein that is important for the repair of the numerous, programmed deoxyribonucleic acid double-strand breaks (DSBs) that occur early in the meiotic prophase.[ PMID:18293007