Home
Product
Protein
Recombinant Proteins
Recombinant Arabidopsis thaliana DNA mismatch repair protein Msh2 (MSH2), partial

Recombinant Arabidopsis thaliana DNA mismatch repair protein Msh2 (MSH2), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
Have Questions?	Leave a Message or Start an on-line Chat

Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

MSH2

Uniprot NO.

O24617

Alternative Names

MSH2; At3g18524; MYF24.25; DNA mismatch repair protein MSH2; AtMSH2; MutS protein homolog 2

Species

Arabidopsis thaliana (Mouse-ear cress)

Source

Yeast

Expression Region

1-937

Target Protein Sequence

MEGNFEEQNK LPELKLDAKQ AQGFLSFYKT LPNDTRAVRF FDRKDYYTAH GENSVFIAKT YYHTTTALRQ LGSGSNALSS VSISRNMFET IARDLLLERN DHTVELYEGS GSNWRLVKTG SPGNIGSFED VLFANNEMQD TPVVVSIFPS FHDGRCVIGM AYVDLTRRVL GLAEFLDDSR FTNLESSLIA LGAKECIFPA ESGKSNECKS LYDSLERCAV MITERKKHEF KGRDLDSDLK RLVKGNIEPV RDLVSGFDLA TPALGALLSF SELLSNEDNY GNFTIRRYDI GGFMRLDSAA MRALNVMESK TDANKNFSLF GLMNRTCTAG MGKRLLHMWL KQPLVDLNEI KTRLDIVQCF VEEAGLRQDL RQHLKRISDV ERLLRSLERR RGGLQHIIKL YQSTIRLPFI KTAMQQYTGE FASLISERYL KKLEALSDQD HLGKFIDLVE CSVDLDQLEN GEYMISSSYD TKLASLKDQK ELLEQQIHEL HKKTAIELDL QVDKALKLDK AAQFGHVFRI TKKEEPKIRK KLTTQFIVLE TRKDGVKFTN TKLKKLGDQY QSVVDDYRSC QKELVDRVVE TVTSFSEVFE DLAGLLSEMD VLLSFADLAA SCPTPYCRPE ITSSDAGDIV LEGSRHPCVE AQDWVNFIPN DCRLMRGKSW FQIVTGPNMG GKSTFIRQVG VIVLMAQVGS FVPCDKASIS IRDCIFARVG AGDCQLRGVS TFMQEMLETA SILKGASDKS LIIIDELGRG TSTYDGFGLA WAICEHLVQV KRAPTLFATH FHELTALAQA NSEVSGNTVG VANFHVSAHI DTESRKLTML YKVEPGACDQ SFGIHVAEFA NFPESVVALA REKAAELEDF SPSSMIINNE ESGKRKSRED DPDEVSRGAE RAHKFLKEFA AIPLDKMELK DSLQRVREMK DELEKDAADC HWLRQFL
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

■ Customer Reviews

Submit a Review here

Target Background

Function(From Uniprot)

Component of the post-replicative DNA mismatch repair system (MMR). Forms three different heterodimers: MutS alpha (MSH2-MSH6 heterodimer), MutS beta (MSH2-MSH3 heterodimer) and MutS gamma (MSH2-MSH7 heterodimer) which binds to DNA mismatches thereby initiating DNA repair. MutS alpha and MutS beta recognize single base mismatches and trinucleotide insertion-deletion loops (IDL) in the DNA. MutS gamma recognizes specifically the T/G single base mismatch. Plays a role in DNA homologous recombination repair and has a broad range of anti-recombination effects. Can suppress recombination between divergent direct repeats in somatic cells and possesses an anti-recombination meiotic effect. Is involved in a UV-B-induced DNA damage response pathway.

Gene References into Functions

The expression of AtMutSgamma (MSH7 and MSH2) in Saccharomyces cerevisiae suggest that AtMutSgamma affects yeast genomic stability by recognizing specific mismatches. PMID:23380521
reported that AtMSH2 has a broad range of anti-recombination effects: it suppresses recombination between divergent direct repeats in somatic cells or between homologues from different ecotypes during meiosis PMID:16311517

Hide All

Subcellular Location

Nucleus.

Protein Families

DNA mismatch repair MutS family

Database Links

UNIGENE: At.10475

KEGG: ath:AT3G18524

STRING: 3702.AT3G18524.1

Promotions