Recombinant Arabidopsis thaliana ABC transporter D family member 1 (ABCC1), partial

Product Details

Abbreviation
ABCC1
Purity
>85% (SDS-PAGE)
Target Names
ABCC1
Uniprot NO.
Alternative Names
ABCD1; ACN2; CTS; PED3; PMP2; PXA1; At4g39850; T5J17.20; ABC transporter D family member 1; ABC transporter ABCD.1; AtABCD1; EC 7.6.2.4; Peroxisomal ABC transporter 1; AtPXA1; Protein ACETATE NON-UTILIZING 2; Protein COMATOSE; Protein PEROXISOME DEFECTIVE 3; Ped3p
Species
Arabidopsis thaliana (Mouse-ear cress)
Source
Yeast
Protein Length
Partial
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage Condition
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)
Contributes to the transport of fatty acids and their derivatives (acyl CoAs) across the peroxisomal membrane. Provides acetate to the glyoxylate cycle in developing seedlings. Involved in pollen tube elongation, ovule fertilization, and seeds germination after imbibition (controls the switch between the opposing developmental programs of dormancy and germination), probably by promoting beta-oxidation of storage lipids during gluconeogenesis. Required for biosynthesis of jasmonic acid and conversion of indole butyric acid to indole acetic acid. Confers sensitivity to monofluoroacetic acid (FAc), a toxic acetate analog, and to 2,4-dichlorophenoxybutyric acid (2,4-DB) and indole-3-butyric acid (IBA), two precursors of auxin after beta-oxidation.
Gene References into Functions
  1. Peroxisomal ATP-binding cassette transporter COMATOSE is required for the accumulation of benzoylated secondary metabolites in Arabidopsis seeds, including benzoylated glucosinolates and substituted hydroxybenzoylcholines. PMID:24254312
  2. The Arabidopsis peroxisomal ABC transporter, comatose, complements the Saccharomyces cerevisiae pxa1 pxa2Delta mutant for metabolism of long-chain fatty acids and exhibits fatty acyl-CoA-stimulated ATPase activity. PMID:20659892
  3. PED3 promotes seed germination by suppressing polygalacturonase inhibiting proteins under the control of ABI5. PMID:20345608
  4. pxa1 plants accumulate free fatty acids in dark-treated leaves. Extended dark conditions are lethal for pxa1 plants. PMID:19794119
  5. The role of the transporter COMATOSE in the biosynthesis of Jasmonic acid in A. thaliana leaves is described. [COMATOSE] [CTS] PMID:15761209
  6. CTS has a role following after-ripening within pathways related to the progression of germination prior to radicle emergence. PMID:16844736
  7. Beta-oxidation could play a role in the mobilization of lipids in both pollen and female tissues. Expression of CTS in either male or female tissues was sufficient to support pollen tube growth in vivo. PMID:17468211
  8. Results demonstrate that COMATOSE functions can be separated by mutagenesis and the structural model provides a framework for interpretation of phenotypic data. PMID:19019987
  9. pxa1 mutants are sucrose-dependent and IBA resistant following germination, probably because of a failure to import beta-oxidation substrates into peroxisomes. PMID:11706205

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Subcellular Location
Peroxisome membrane; Multi-pass membrane protein. Glyoxysome membrane; Multi-pass membrane protein.
Protein Families
ABC transporter superfamily, ABCD family, Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily
Database Links

UNIGENE: At.22795

KEGG: ath:AT4G39850

STRING: 3702.AT4G39850.3

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