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Recombinant Shigella flexneri Antitoxin VapB (vapB)

Recombinant Shigella flexneri Antitoxin VapB (vapB)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

vapB

Uniprot NO.

O06663

Alternative Names

vapB; CP0246; Antitoxin VapB

Species

Shigella flexneri

Source

Yeast

Expression Region

1-75

Target Protein Sequence

METTVFLSNR SQAVRLPKAV ALPENVKRVE VIAVGRTRII TPAGETWDEW FDGHSVSTDF MDNREQPGMQ ERESF
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Buffer

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in E.coli neutralizes the effect of cognate toxin VapC. The VapB/VapC complex probably regulates transcription of its own promoter.

Gene References into Functions

VapC (MvpT) of Shigella flexneri 2a virulence plasmid pMYSH6000 (23) is a site-specific tRNase that cleaves initiator tRNA between the anticodon stem and loop. PMID:21502523

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Protein Families

VapB family

Database Links

KEGG: sfl:CP0246

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