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Recombinant Aeropyrum pernix DNA double-strand break repair Rad50 ATPase (rad50), partial

Recombinant Aeropyrum pernix DNA double-strand break repair Rad50 ATPase (rad50), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

rad50

Purity

>85% (SDS-PAGE)

Target Names

rad50

Uniprot NO.

Q9YFZ1

Alternative Names

rad50; APE_0110; DNA double-strand break repair Rad50 ATPase

Species

Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)

Source

Yeast

Expression Region

1-919

Target Protein Sequence

MYVLKRLELR NIMSHFNTSI DFREGFTAIV GRNGAGKSTI LEAILFSITP HQAPRRSSMI SENSSRGEIY LALQSSEGRL LELRNKLIRR GGGTNTEAAI ITLEGRRIAS KPTGYKEEIH KILGLRGLPN PASYIEKAII ISQGGLQTLA EILSEPKELR DLLDAALGYA LLKQAISNIG DVVLGVSPDG SPVKLGSKSI TRLQSGYMTL RNEVLGVDRE IREASKRLEE LEREREELER RARDLESEAK ALQSEIGKLE TMEEMLVNVT SMIRSERSKL DTINTRLRYA ESKISSIDDL EKRRAELRAK ASLAHEVAEL ARLQSRLDKL GRDLEMIRDA VEKLEVSRRL KEIESARREA ENRLLEARSS IKEEQRRYTL LDYRVTRGRS IVTNIRRVLS ECRSKDLCGS EKPESVLERL DAVINDLESK ARALDQEASA LEAEARRLVQ ALSMLEESGG SARCPVCGAE LPPGRAEAIA RHYRHEAERL RKAAKEKAAE AEKARAEASR LQDKRRRIEL LLSRLNQLEE GLRELGFQTP EDLAKAEQKL RMLRERLEEL RKLENSLEEK VRNLSREEVA LREAKTRALE VLQRLGIKEE EAREKLKTLS SESKKLERML VSKAEDLATR LGITAYRSLD DLLEKAREAL EGVDKELSAI ERRLEEARRL KEEAAKLKWE AEQVMKRLEE LEAEEKKLRK EVSRKSEIEA RLKEVQNTLA ELDDRISRID REMGELQTRI REMKSRKASG EEALKLYLPA AASRRIMEEI GEIAYRRLLA VLEDEMNDIL SRFNLDVAGV EIREKAAREI EVKAIGGNGA YRPLEAVSGG ERTVLALSFV LALNKAVGGK LGFLALDEPT ANLDEDRRRS LVEVLRGISV EGLVRQLVVV THHEDVRDYA DTICLVTRTQ QGSRVECTY
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex.

Protein Families

SMC family, RAD50 subfamily

Database Links

KEGG: ape:APE_0110

STRING: 272557.APE_0110

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