YWHAH Antibody

Code: CSB-PA026289GA01HU

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Size:

100μl

US$600

Quantity:

Species Reactivity: Human,Mouse,Rat

Raised in: Rabbit

Application: ELISA,WB

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Target Background

Product Details

Uniprot NO.

Q04917

Target Names

YWHAH

Alternative Names

14 3 3 protein eta antibody; 14-3-3 eta antibody; 14-3-3 protein eta antibody; 1433F_HUMAN antibody; Brain protein 14-3-3; eta isoform antibody; HGNC:12853 antibody; Protein AS1 antibody; Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein 1 antibody; Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein eta polypeptide antibody; Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein; eta isoform antibody; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein; eta antibody; Tyrosine 3/tryptophan 5 monooxygenase activation protein eta polypeptide antibody; YWHA 1 antibody; YWHA1 antibody; Ywhah antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human YWHAH

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB

Protocols

ELISA Protocol Western Blotting(WB) Protocol

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

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Target Background

Function(From Uniprot)

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.

Gene References into Functions

Results show that YWHAZ amplification indicates a better survival trend in bladder cancer. Its knockdown promotes both in vitro and in vivo tumorigenesis in bladder cancer and may be a novel biomarker for bladder cancer. PMID:29512774
The impact of AKT1 on glucocorticoid receptor (GR)-induced transcriptional activity in cooperation with phospho-serine/threonine-binding protein 14-3-3, was examined. PMID:27717743
14-3-3 eta isoform colocalizes TDP-43 on the coarse granules in the anterior horn cells of patients with sporadic amyotrophic lateral sclerosis. PMID:27256400
Extracellular 14-3-3eta activates key signalling cascades and induces factors associated with the pathogenesis of rheumatoid arthritis PMID:24751211
This study identified YWHAH significantly associated loci with a biologically plausible role in schizophrenia. PMID:24507884
14-3-3eta may be required for mitotic progression and may be considered as a novel anti-cancer strategy in combination with microtubule inhibitors. PMID:22562251
This is the first genetic association study of YWHAH with sporadic Creutzfeldt-Jakob disease populations. PMID:21739144
relocation of p33ING1b from the nucleus to the cytoplasm, where the protein is tethered by 14-3-3eta, participates in tumorigenesis and progression in HNSCC PMID:21432775
The 14-3-3 eta, beta, gamma and sigma isoforms were negatively expressed in meningioma PMID:20388496
phosphorylation of 14-3-3 binding site of myeloid leukemia factor 1 by MADM PMID:12176995
Data demonstrate that 14-3-3 proteins are colocalized with Lewy bodies in Parkinson disease, but there was no specific staining for the 14-3-3 eta subunit. PMID:12480176
gremlin 1 is overexpressed in human cancers and interacts with YWHAH protein PMID:16545136
The association of YWHAH with bipolar disorder in a large sample, consisting of 1211 subjects from 318 nuclear families including 554 affected offspring, was investigated. PMID:19160447