VEGFB Antibody

Code: CSB-PA025834LA01HU

Rate （5.0）
Review （1）

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US$83

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Species Reactivity: Human, Mouse, Rat

Raised in: Rabbit

Application: ELISA, WB, IHC

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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot NO.

P49765

Target Names

VEGFB

Alternative Names

Vascular endothelial growth factor B antibody; Vascular endothelial growth factor-related factor antibody; VEGF B antibody; VEGF related factor antibody; VEGF-B antibody; VEGF-related factor antibody; Vegfb antibody; VEGFB_HUMAN antibody; VEGFL antibody; VRF antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant Human Vascular endothelial growth factor B protein (22-207AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol Western Blotting(WB) Protocol Immunohistochemistry (IHC) Protocol

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

Antibody FAQs

Images

Western Blot
Positive WB detected in: Rat heart tissue, Rat spleen tissue, Mouse heart tissue, Mouse liver tissue, Mouse kidney tissue, Mouse brain tissue
All lanes: VEGFB antibody at 3.5μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 22 kDa
Observed band size: 28 kDa
Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA025834LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA025834LA01HU at dilution of 1:100

Customer Reviews and Q&A

■ Customer Reviews

Average Rating:

5.0 - 1 reviews

Submit a Review here

Applications : Western Blot (WB)

Sample type: tissue

Sample dilution: 1：2000

Review: I used the CSB-PA025834LA01HU antibody for WB detection. The mouse liver tissue tested was processed according to the conventional protein extraction process without special processing. The results are as follows, not bad.

By Anonymous

Target Background

Function(From Uniprot)

Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis.

Gene References into Functions

High plasma VEGF-B levels are associated with type 2 diabetes mellitus. PMID:28523459
Data from clinical studies point out the changes in circulating or tissue expression levels of VEGF-B in obese compared with lean patients. PMID:28798193
Cardiac transgenic vascular endothelial growth factor-B overexpression failed to protect heart transplants from ischemia-reperfusion injury. PMID:27588416
renal VEGF-B expression correlates with the severity of Diabetic Kidney Disease. PMID:28190774
Data show that metformin treatment reduces serum vascular endothelial growth factor B (VEGF-B) levels and ameliorates insulin resistance. PMID:26387747
Frameshift mutations of VEGFB gene is associated with stomach and colorectal cancers. PMID:25633991
fluid shear stress induces the synthesis of Insulin growth factor-2 and vascular endothelial growth factor (VEGF) B and D, which in turn transactivate MMP-12. PMID:25435370
MMP9 may activate VEGF-B via PI3K/Akt signaling pathway. PMID:25424698
Roles of vascular endothelial growth factor in amyotrophic lateral sclerosis. PMID:24987705
Low VEGFB and VEGFD gene expression is associated with early-stage non-small cell lung cancer. PMID:24145997
Our study suggested that VEGF-B was an angiogenesis factor in vitro and that ERK1/2 and p38-related signaling pathways were involved in these VEGF-B activities. PMID:24374930
VEGF-B has possible roles in cardiac protection, energy metabolism support, and neuroprotectin [review] PMID:24987005
High VEGF-B levels might correlate with the presence of hyperlipidemia and target organ damage in type 2 diabetic patients. PMID:25001655
High VEGFB expression is associated with bone marrow metastasis in neuroblastoma. PMID:23553333
VEGF-B might be an important ligand in the signalling between the tumor and preexisting blood vessels to ensure a functional blood supply for tumor survival. PMID:23417498
we report significant associations with overall survival and distant failure for certain VEGF(VEGF-B) family members. PMID:23728940
Data indicate that three miRs (miR-484, -642, and -217) were able to predict chemoresistance and vasculature of serous epithelial ovarian carcinomas through the regulation of the VEGFB and VEGFR2 pathways. PMID:23697367
Expression of VEGF-B genes in glioma cell lines U87 is significantly changed under hypoxia and ischemic conditions. PMID:23350126
In WT1 mutant cells, reduced VEGF(165)b was due to lack of WT1-mediated transcriptional repression of the splicing-factor kinase SRPK1 PMID:22172722
analysis of binding of vascular endothelial growth factor-B by VEGFR-1(D2) PMID:20501651
TIMP3 blocks the binding of VEGF to VEGF receptor-2 and inhibits downstream signaling and angiogenesis. PMID:12652295
Results describe the crystal structure of human vascular endothelial growth factor-B (VEGF-B) and present a predicted model for the association of VEGF-B with the second domain of its receptor, VEGFR-1. PMID:16616187
Basophils could play a role in angiogenesis and inflammation through the expression of several forms of VEGF-B and their receptors. PMID:17082651
VEGFB, and receptor were highly expressed in dysplastic neurons. IR in astroglial and balloon cells was observed for VEGFA and its receptors Double-labeling also showed expression of VEGFA, VEGFB and VEGFR-1 in cells of the microglia/macrophage lineage. PMID:18317782
VEGF-B appears to have a relatively restricted angiogenic activity in the ischemic heart. PMID:18511699
Increased VEGFB expression is associated with hepatocellular carcinoma PMID:18537151
Overexpression of vascular endothelial growth factor-B in mouse heart alters cardiac lipid metabolism and induces myocardial hypertrophy. PMID:18757827
The structural features of the 'highly ordered' interaction of the Fab fragment of the antibody (Fab-2H10) with VEGF-B, is presented. PMID:18930733
VEGF-B mRNA was not expressed either in normal urothelium or in bladder cancer. PMID:19424629