Tf Antibody, Biotin conjugated

Code: CSB-PA856363LD01MO

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Size:

50μl100μl

US$166

Quantity:

Species Reactivity: Mouse

Raised in: Rabbit

Application: ELISA

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Target Background

Product Details

Uniprot NO.

Q921I1

Target Names

Alternative Names

Tf antibody; Trf antibody; Serotransferrin antibody; Transferrin antibody; Beta-1 metal-binding globulin antibody; Siderophilin antibody

Raised in

Rabbit

Species Reactivity

Mouse

Immunogen

Recombinant Mouse Serotransferrin protein (401-697AA)

Immunogen Species

Mus musculus (Mouse)

Conjugate

Biotin

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Tested Applications

ELISA

Protocols

ELISA Protocol

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

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Target Background

Function(From Uniprot)

Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.

Gene References into Functions

the value of transferrin receptors (TfRs)/cell reveals a 100-fold increase in the number of TfRs per bEnd3 cells compared to human umbilical vein cells. PMID:27100851
Identification of multiple transferrin species in the spleen and serum from mice with collagen-induced arthritis which may reflect changes in transferrin glycosylation associated with disease activity: The role of CD38. PMID:26639305
Transcytosis and brain uptake of transferrin-containing nanoparticles by tuning avidity to transferrin receptor. PMID:23650374
Together, these data indicate that Lcn2, in combination with transferrin, confines Klebsiella pneumoniae to the airways and prevents invasion into tissue containing the pulmonary vasculature. PMID:23169997
Transferrin(hpx/hpx) Hemojuvelin(+/+) and Transferrin(hpx/hpx) Hemojuvelin(-/-) phenotypes did not differ markedly, but RBC transfusions increased hepcidin levels in Transferrin(hpx/hpx) Hemojuvelin(+/+) but not Transferrin(hpx/hpx) Hemojuvelin(-/-)mice. PMID:21993681
These results indicate that CALM is required for erythroid maturation and transferrin internalization in mice. PMID:22363754
Neurodegenerative conditions involving iron-mediated toxicity may be due to a failure of iron transport or storage mechanisms, rather than to the presence of high levels of non-transferrin-bound iron. PMID:20431983
Apotransferrin mitigates the neurotoxicity of hemoglobin in a cell culture model of intracerebral hemorrhage. PMID:21034753
Descibed is the 2.4 A structure of inhibitor of carbonic anhydrase from a pseudomerohedral twinned crystal: a member of the transferrin superfamily. PMID:20572014
transferrin receptor 2 and HFE are involved in holotransferrin-dependent signaling for the regulation of furin which involved Erk phosphorylation. Furin in turn may control hepcidin expression. PMID:20634490
hepcidin expression in hypotransferrinemic mice is regulated both by transferrin-restricted erythropoiesis and by transferrin through a mechanism independent of its role in erythropoiesis PMID:20956801
These data show that mycobacteria reside in the Rab11(+) endocytic recycling pathway, thereby retaining access to metabolizing transferrin and avoiding endocytosed immunoproteins like Lcn2. PMID:20121435
during later times postinfection (1.5 to 3 h), the virus meets up with transferrin in the Rab11-positive recycling endosome PMID:16611921
Transsferrin overexpression has negative effects on testicular function and that transfserrin levels require strict regulation in the testis. PMID:16998850
developing erythroid cells, which are taking up vast amounts of Fe, deliver the metal directly from transferrin-containing endosomes to mitochondria PMID:17376890
The role of transferrin in glial protection was investigated. PMID:18509548
Data show that the transferrin receptor TfR1 provided transferrin to the ureteric bud, but not to the capsule or the stroma, and that Scara5 bound serum ferritin and then stimulated its endocytosis from the cell surface with consequent iron delivery. PMID:19154717