TOX2 Antibody

CSB-PA024074LA01HU

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US$83

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Species Reactivity: Human

Raised in: Rabbit

Application: ELISA, WB

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Product Details
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Target Background

Product Details

Uniprot NO.

Q96NM4

Target Names

TOX2

Alternative Names

C20orf100 antibody; Chromosome 20 open reading frame 100 antibody; dJ1108D11.2 antibody; dJ495O3.1 antibody; GCX 1 antibody; GCX1 antibody; Granulosa cell HMG box protein 1 antibody; MGC15880 antibody; TOX high mobility group box family member 2 antibody; TOX2 antibody; TOX2_HUMAN antibody; Weakly similar to NONHISTONE CHROMOSOMAL PROTEIN 6A [S.cerevisiae] antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human TOX high mobility group box family member 2 protein (303-417AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Tested Applications

ELISA, WB

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Protocols

ELISA Protocol Western Blotting(WB) Protocol

Datasheet & COA

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Images

Western Blot
Positive WB detected in: K562 whole cell lysate, Raji whole cell lysate, Jurkat whole cell lysate
All lanes: TOX2 antibody at 4.3µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 52, 55, 50, 54 kDa
Observed band size: 52, 50 kDa

Description

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Target Background

Function

Putative transcriptional activator involved in the hypothalamo-pituitary-gonadal system.

Gene References into Functions

A haplotype block across a 24-kb region within the TOX2 gene reached genome-wide significance in haplotype-block-based regional heritability mapping. Single-SNP- and haplotype-based association tests demonstrated that five of nine genotyped SNPs and two haplotypes within this block were significantly associated with major depressive disorder. PMID:28153336
TOX2 plays a crucial role in controlling normal NK cell development by acting upstream of TBX21 transcriptional regulation PMID:25352127
A novel aberrantly hypermethylated CpG island in cancer was discovered within the TOX2 promoter. TOX2 was unmethylated in normal cells. Expression of two novel TOX2 transcripts was significantly reduced in primary lung tumors. PMID:22496870
Identification and functional analysis of the rat Gcx1 ortholog. PMID:14764631