TEAD2 Antibody

Code: CSB-PA070034

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50μg100μg

US$119

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Species Reactivity: Human,Mouse

Raised in: Rabbit

Application: WB, IHC, IF, ELISA

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Product Details
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Target Background

Product Details

Uniprot NO.

Q15562

Target Names

TEAD2

Alternative Names

Embryonic TEA domain containing factor antibody; Etdf antibody; ETEF 1 antibody; ETF antibody; TEA domain family member 2 antibody; TEAD 2 antibody; TEAD-2 antibody; TEAD2 antibody; Tead2 protein (TEA domain family member 2 (Mapped), isoform CRA_b) antibody; TEAD2_HUMAN antibody; TEF 4 antibody; TEF4 antibody; Transcriptional enhancer factor 4 antibody; Transcriptional enhancer factor TEF 4 antibody; Transcriptional enhancer factor TEF-4 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Synthesized peptide derived from the Internal region of Human TEF-4.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Tested Applications

WB, IHC, IF, ELISA

Protocols

Western Blotting(WB) Protocol Immunohistochemistry (IHC) Protocol Immunofluorescence (IF) Protocol ELISA Protocol

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

Antibody FAQs

Images

Western Blot analysis of mouse-brain cells using TEF-4 Polyclonal Antibody

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Target Background

Function(From Uniprot)

Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3'). May be involved in the gene regulation of neural development. Binds to the M-CAT motif.

Gene References into Functions

TAZ negatively regulate transcription of DeltaNp63 through TEAD1,2,3 and 4 transcription factors. PMID:25995450
structural and functional analysis of the YAP-binding domain of human TEAD2 PMID:20368466

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Subcellular Location

Nucleus.

Database Links

HGNC: 11715

UNIGENE: Hs.515534

KEGG: hsa:8463

STRING: 9606.ENSP00000310701

OMIM: 601729

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