SYCP1 Antibody

Code: CSB-PA225456

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Size:

50μl100μl

US$166

Quantity:

Species Reactivity: Human

Raised in: Rabbit

Application: ELISA,IHC

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Target Background

Product Details

Uniprot NO.

Q15431

Target Names

SYCP1

Alternative Names

Cancer/testis antigen 8 antibody; CT8 antibody; HOM TES 14 antibody; MGC104417 antibody; SCP 1 antibody; SCP-1 antibody; SCP1 antibody; SYCP 1 antibody; Sycp1 antibody; SYCP1_HUMAN antibody; Synaptonemal complex protein 1 antibody; Testicular tissue protein Li 191 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthetic peptide of Human SYCP1

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Tested Applications

ELISA,IHC

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

Antibody FAQs

Images

The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA225456(SYCP1 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)

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Target Background

Function(From Uniprot)

Major component of the transverse filaments of synaptonemal complexes, formed between homologous chromosomes during meiotic prophase. Required for normal assembly of the central element of the synaptonemal complexes. Required for normal centromere pairing during meiosis. Required for normal meiotic chromosome synapsis during oocyte and spermatocyte development and for normal male and female fertility.

Gene References into Functions

Crystal structure of C-terminal coiled-coil domain of SYCP1 reveals non-canonical anti-parallel dimeric structure of transverse filament at the synaptonemal complex. PMID:27548613
crystal structure of the middle part of the human synaptonemal complex protein 1 coiled-coil domain PMID:26323297
SYCP1, cTAGE1, and GTSF1 are expressed in cutaneous T-cell lymphoma, but not in normal skin or benign inflammatory dermatoses. PMID:24850846
Cancer-Testis Antigen SCP-1 mRNA is expressed in some nasopharyngeal carcinoma. PMID:17608150
an epitope derived from the cancer testis antigen HOM-TES-14/SCP1 and presented by dendritic cells to circulating CD4+ T cells PMID:16030183