Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Western Blot
Positive WB detected in: Spinacia oleracea leaf tissue
All lanes: SUN1 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 52 kDa
Observed band size: 52 kDa
Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Required for the maintenance and/or formation of polarized nuclear shape in root hairs. Modulates the anchoring and mobility of WIP proteins and RANGAP1 in the nuclear envelope (NE). In association with SUN2, may be involved in telomere attachment to nuclear envelope in the prophase of meiosis. As component of the SUN-WIP-WIT2-KAKU1 complex, mediates the transfer of cytoplasmic forces to the nuclear envelope (NE), leading to nuclear shape changes.
Gene References into Functions
Results indicate that AtSUN1 contain the highly conserved C-terminal SUN domain, localize to and show low mobility in the nuclear envelope (NE), particularly in the inner nuclear membrane.PMID:19807882
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Subcellular Location
Nucleus inner membrane; Single-pass type II membrane protein. Cytoplasm, cytoskeleton, phragmoplast. Endoplasmic reticulum membrane; Single-pass type II membrane protein. Nucleus envelope.
Tissue Specificity
Expressed in roots, hypocotyls, cotyledons and leaves and inflorescences.