SHKBP1 Antibody

Code: CSB-PA021271GA01HU

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Size:

100μl

US$600

Quantity:

Species Reactivity: Human,Mouse,Rat

Raised in: Rabbit

Application: ELISA,WB

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Target Background

Product Details

Uniprot NO.

Q8TBC3

Target Names

SHKBP1

Alternative Names

PP203 antibody; Sb1 antibody; SH3KBP1 binding protein 1 antibody; SH3KBP1-binding protein 1 antibody; SHKB1_HUMAN antibody; SHKBP1 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human SHKBP1

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB

Protocols

ELISA Protocol Western Blotting(WB) Protocol

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

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Target Background

Function(From Uniprot)

Inhibits CBL-SH3KBP1 complex mediated down-regulation of EGFR signaling by sequestration of SH3KBP1. Binds to SH3KBP1 and prevents its interaction with CBL and inhibits translocation of SH3KBP1 to EGFR containing vesicles upon EGF stimulation.

Gene References into Functions

SHKBP1 disturbed the translocation of CIN85 to EGFR-containing vesicles. PMID:21830225
hSB1 may function as a regulator of cathepsin B-mediated apoptosis. PMID:16733801

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Subcellular Location

Lysosome.

Protein Families

KCTD3 family

Tissue Specificity

Widely expressed.

Database Links

HGNC: 19214

UNIGENE: Hs.26506

KEGG: hsa:92799

STRING: 9606.ENSP00000291842