SH3GLB2 Antibody

Code: CSB-PA868296ESR1HU

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Size:

20μl50μl100μl

US$83

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Species Reactivity: Human, Mouse

Raised in: Rabbit

Application: ELISA, WB, IHC

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Target Background

Product Details

Uniprot NO.

Q9NR46

Target Names

SH3GLB2

Alternative Names

Endophilin B2 antibody; Endophilin-B2 antibody; OTTHUMP00000022320 antibody; PP6569 antibody; PP9455 antibody; Retinoid receptor induced gene 1 antibody; RRIG1 antibody; SH3 containing protein SH3GLB2 antibody; SH3 domain GRB2 like endophilin B2 antibody; SH3 domain-containing GRB2-like protein B2 antibody; SH3GLB2 antibody; SHLB2_HUMAN antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human Endophilin-B2 protein (1-250AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

Antibody FAQs

Images

Western blot
All lanes: SH3GLB2 antibody at 5.5μg/ml + Mouse liver tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 44, 45 kDa
Observed band size: 44 kDa
Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA868296ESR1HU at dilution of 1:100

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Target Background

Gene References into Functions

Here the authors report that Endophilin B2, similarly to Endophilin B1, plays an indispensable role in mitochondria sequestration and inner mitochondrial membrane (IMM) protein degradation during mitophagy. PMID:27112121
Data (including data from studies in knockout mice) suggest that SH3GLB2 regulates trafficking of endocytic vesicles and autophagosomes to late endosomes or lysosomes; despite having an intracellular localization and tissue distribution similar to endophilin B1, endophilin B2 is dispensable for mitochondrial apoptosis. PMID:28455444
the potential importance of the endophilin B2-plectin complex in the biological functions depending on nuclear migration and positioning. PMID:23921385
identified a nonmutated HLA-A2-binding epitope in the human ortholog SH3GLB2, which primed T cells from healthy HLA-A2(+) individuals PMID:18303116