RPL26 Antibody, Biotin conjugated

Code: CSB-PA020207LD01HU

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Size:

50μg100μg

US$166

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Species Reactivity: Human

Raised in: Rabbit

Application: ELISA

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Product Details
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Target Background

Product Details

Uniprot NO.

P61254

Target Names

RPL26

Alternative Names

tibody; 60S ribosomal protein L26 antibody; 60S ribosomal protein L26 like 1 antibody; DBA11 antibody; FLJ46904 antibody; L26 antibody; OTTHUMP00000135333 antibody; PTB associated splicing factor antibody; Ribosomal protein L26 antibody; Ribosomal protein L26 homolog antibody; Ribosomal protein L26 like 1 antibody; Ribosomal protein L26 pseudogene 1 antibody; RL26_HUMAN antibody; rpl26 antibody; RPL26P1 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human 60S ribosomal protein L26 protein (48-143AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Biotin

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Tested Applications

ELISA

Protocols

ELISA Protocol

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

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Target Background

Function(From Uniprot)

Component of the large ribosomal subunit.

Gene References into Functions

ionizing radiation (IR) inhibits the activity of SMG1, a phosphoinositide-3-kinase-like kinase family member, reducing the binding of SMG1 to a specific region near exon 9 of p53 precursor mRNA and promoting the binding of ribosomal protein L26 (RPL26) to p53 pre-mRNA PMID:28288992
In colorectal tumor cells RPL26 regulates p73 expression via two distinct mechanisms: protein stability and mRNA translation. PMID:27825141
Six1 regulates p53 via a dual mechanism involving upregulation of microRNA-27a and downregulation of RPL26. PMID:26687066
The results showed that knockdown of RPL26 or RPL29 expression significantly suppressed cell proliferation, induced cell arrest at G0/G1 phase and enhanced cell apoptosis PMID:22868929
Northern Blot Together with RPL5, RPL11, and RPS7, RPL26 is the fourth RP regulating p53 activity that is linked to diamond-blackfan anemia. PMID:22431104
suggest a model in which the base pairings in the p53 UTR interaction regions are critical for both translational repression and stress induction of p53 by NCL and RPL26 PMID:22433872
Mdm2 binds L26 and drives its polyubiquitylation and proteasomal degradation. PMID:18951086