RBM6 Antibody

Code: CSB-PA006412

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Size:

50μg100μg

US$119

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Species Reactivity: Human,Mouse

Raised in: Rabbit

Application: WB, IHC, IF, ELISA

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Target Background

Product Details

Uniprot NO.

P78332

Target Names

RBM6

Alternative Names

3G2 antibody; 4930506F14Rik antibody; DEF 3 antibody; DEF3 antibody; DKFZp686B0877 antibody; FLJ36517 antibody; g16 antibody; HLC 11 antibody; KIAA4015 antibody; Lung cancer antigen NY LU 12 antibody; Lung cancer antigen NY-LU-12 antibody; Lung cancer protooncogene 11 antibody; mKIAA4015 antibody; NY LU 12 antibody; Protein G16 antibody; RBM6 antibody; RBM6/RBM5 fusion antibody; RBM6_HUMAN antibody; RGD1560367 antibody; RNA binding motif protein 6 antibody; RNA-binding motif protein 6 antibody; RNA-binding protein 6 antibody; RNA-binding protein DEF-3 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Synthesized peptide derived from the C-terminal region of Human DEF-3.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Tested Applications

WB, IHC, IF, ELISA

Protocols

Western Blotting(WB) Protocol Immunohistochemistry (IHC) Protocol Immunofluorescence (IF) Protocol ELISA Protocol

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

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Target Background

Function(From Uniprot)

Specifically binds poly(G) RNA homopolymers in vitro.

Gene References into Functions

Antagonizes the effects of RBM5, RBM6, and RBM10 in cell colony formation. PMID:24332178
identified a novel fusion of the RNA binding motif 6 (RBM6) gene to CSF1R gene generated presumably by a t(3;5)(p21;q33) translocation that induced a myeloid proliferative disease with features of megakaryoblastic leukemia in a murine transplant model PMID:17360941
RBM6 mRNA experiences altered co-transcriptional gene regulation in certain cancers. RBM6-RBM5 transcription-induced chimerism might be a process that is linked to the tumour-associated increased transcriptional activity of the RBM6 gene PMID:17908320

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Subcellular Location

Nucleus.

Tissue Specificity

Ubiquitous in adults.

Database Links

HGNC: 9903

UNIGENE: Hs.696735

KEGG: hsa:10180

STRING: 9606.ENSP00000266022

OMIM: 606886

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