PRKAR1B Antibody

Code: CSB-PA003797

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Size:

50μg100μg

US$119

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Species Reactivity: Human,Mouse,Rat

Raised in: Rabbit

Application: WB, IHC, ELISA

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Target Background

Product Details

Uniprot NO.

P31321

Target Names

PRKAR1B

Alternative Names

cAMP dependent protein kinase type I beta regulatory subunit antibody; cAMP-dependent protein kinase type I-beta regulatory subunit antibody; KAP1_HUMAN antibody; PKARI beta antibody; PRKAR 1 antibody; PRKAR 1B antibody; PRKAR1 antibody; Prkar1b antibody; PRKAR1B protein antibody; Protein kinase cAMP dependent regulatory type I beta antibody; RIbeta antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthesized peptide derived from the Internal region of Human PKA Iβ reg.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Tested Applications

WB, IHC, ELISA

Protocols

Western Blotting(WB) Protocol Immunohistochemistry (IHC) Protocol ELISA Protocol

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

Antibody FAQs

Images

Western Blot analysis of COLO205 cells using PKA Iβ reg Polyclonal Antibody
Western Blot analysis of K562 cells using PKA Iβ reg Polyclonal Antibody

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■ Customer Reviews

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Target Background

Function(From Uniprot)

Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells.

Gene References into Functions

No pathogenic PRKAR1B mutations were found in early onset familial dementia patients in a Dutch cohort. PMID:25108559
This study demonistrated that PRKAR1B mutation associated with a new neurodegenerative disorder with unique pathology. PMID:24722252
The paired-like homeodomain protein, Arix, mediates protein kinase A-stimulated dopamine beta-hydroxylase gene transcription through its phosphorylation status PMID:11943777

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Subcellular Location

Cell membrane.

Protein Families

CAMP-dependent kinase regulatory chain family

Tissue Specificity

Four types of regulatory chains are found: I-alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.

Database Links

HGNC: 9390

UNIGENE: Hs.520851

KEGG: hsa:5575

STRING: 9606.ENSP00000353415

OMIM: 176911

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