Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Nuclear receptor coactivator. May play a role in signal transduction.
Gene References into Functions
PNRC and Grb2, by interacting with each other, can suppress nuclear receptor-mediated regulation and growth factor-mediated regulation in human breast tissuePMID:15122321
Functional analysis of the 5' flanking region of the human PNRC gene by deletion mutagenesis, transient transfection and luciferase assays revealed that the -123/+27 region is the minimal promoter of the human PNRC gene.PMID:18281297
Three human PNRC splicing variants designated PNRC1c, PNRC1d and PNRC1f, are identified.PMID:18703122
RFX1 specifically bind to promoter region and negatively regulate the transcription of the human PNRC gene.PMID:19334528