PHKG2 Antibody

Code: CSB-PA017928ESR2HU

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Size:

20μl50μl100μl

US$83

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Species Reactivity: Human

Raised in: Rabbit

Application: ELISA, WB, IHC

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Product Details
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Target Background

Product Details

Uniprot NO.

P15735

Target Names

PHKG2

Alternative Names

PHKG2Phosphorylase b kinase gamma catalytic chain antibody; liver/testis isoform antibody; PHK-gamma-LT antibody; PHK-gamma-T antibody; EC 2.7.11.19 antibody; PSK-C3 antibody; Phosphorylase kinase subunit gamma-2 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Phosphorylase b kinase gamma catalytic chain, liver/testis isoform protein (237-406AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

Antibody FAQs

Images

Western blot
All lanes: PHKG2 antibody at 3.4µg/ml + HepG2 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 47, 44 kDa
Observed band size: 47 kDa
Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA017928ESR2HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA017928ESR2HU at dilution of 1:100

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Target Background

Function(From Uniprot)

Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. May regulate glycogeneolysis in the testis. In vitro, phosphorylates PYGM.

Gene References into Functions

These cases add to the current knowledge of clinical variability in patients with PHKG2 mutations. Long term studies, involving follow-up of these patients into adulthood, are needed PMID:24389071
Patients with PHKG2 mutations have a severe hepatic phenotype within the heterogeneous GSD IX disorder. A defect in PHKG2 should be considered in patients with suspected glycogenosis associated with significant liver fibrosis and cirrhosis. PMID:24326380
PHKG2 mutations are associated with Glycogen storage disease type IX PMID:17689125

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Protein Families

Protein kinase superfamily, CAMK Ser/Thr protein kinase family

Database Links

HGNC: 8931

UNIGENE: Hs.65735

KEGG: hsa:5261

STRING: 9606.ENSP00000455607

OMIM: 172471

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