P2RX5 Antibody

Code: CSB-PA017323GA01HU

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Size:

100μl

US$600

Quantity:

Species Reactivity: Human

Raised in: Rabbit

Application: ELISA,WB

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Target Background

Product Details

Uniprot NO.

Q93086

Target Names

P2RX5

Alternative Names

ATP receptor antibody; ATP receptor subunit antibody; Ionotropic ATP receptor P2X5 antibody; LRH 1 antibody; LRH1 antibody; Lymphoid restricted histocompatibility antigen 1 antibody; MGC47755 antibody; P2rx5 antibody; P2RX5_HUMAN antibody; P2X purinoceptor 5 antibody; P2X5 antibody; P2X5R antibody; Purinergic receptor antibody; Purinergic receptor P2X ligand gated ion channel 5 antibody; Purinergic receptor P2X5 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Human P2RX5

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB

Protocols

ELISA Protocol Western Blotting(WB) Protocol

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

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Target Background

Function(From Uniprot)

Receptor for ATP that acts as a ligand-gated ion channel.

Gene References into Functions

The amino acid transporter PAT2 and the purinergic receptor P2RX5 are cell surface markers expressed in classical brown and beige adipocytes. PMID:25080478
These data indicate a functional role of the human P2RX5 splice variant in T cell activation and immunoregulation. PMID:25181038
These findings provide a rationale for use of LRH-1 as immunotherapeutic target antigen to treat residual or persisting myeloid malignancies after allogeneic stem cell transplantation PMID:19074734
Purinergic receptor P2X5 binds to adenosine triphosphate (ATP) to form a molecular complex with ASIC3 (acid-sensing ion channel number 3) to detect muscle ischemia. PMID:21092862
findings indicate that most humans express only a nonfunctional isoform of P2X5, which is in stark contrast to what is seen in other vertebrate species in which P2X5 has been studied, from which only the full-length isoform is known PMID:20223879
Different purinergic receptors have different functional roles in human epidermis with P2Y1 and P2Y2 receptors controlling proliferation, while P2X5 and P2X7 receptors control early differentiation, terminal differentiation and death of keratinocytes. PMID:12787128
Non-melanoma skin cancers express functional purinergic receptors and that P2X7 receptor agonists significantly reduce cell numbers in vitro. PMID:12880424
a P2X5 frameshift mutation has a role in response to treatment of chronic myeloid leukemia PMID:16322791
Increased keratinocyte P2X(5) receptor activity may, in part, be accountable for epidermal thinning in chronic venous insufficiency. PMID:16967306
analysis of topology, helix-helix interactions, and oligomerization of P2X5 subunits PMID:17001079
LRH-1 is aberrantly expressed on solid tumor cells PMID:18719914