NR6A1 Antibody

Code: CSB-PA016067GA01HU

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Size:

100μl

US$600

Quantity:

Species Reactivity: Human,Mouse,Rat

Raised in: Rabbit

Application: ELISA,WB

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Target Background

Product Details

Uniprot NO.

Q15406

Target Names

NR6A1

Alternative Names

GCNF 1 antibody; GCNF antibody; GCNF1 antibody; Germ cell nuclear factor antibody; hGCNF antibody; hRTR antibody; NR 61 antibody; NR61 antibody; nr6a1 antibody; NR6A1_HUMAN antibody; Nuclear receptor subfamily 6 group A member 1 antibody; Orphan nuclear receptor NR6A1 antibody; Retinoic acid receptor related testis associated receptor antibody; Retinoid receptor related testis specific receptor antibody; Retinoid receptor-related testis-specific receptor antibody; RTR antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human NR6A1

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB

Protocols

ELISA Protocol Western Blotting(WB) Protocol

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

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Target Background

Function(From Uniprot)

Orphan nuclear receptor. Binds to a response element containing the sequence 5'-TCAAGGTCA-3'. May be involved in the regulation of gene expression in germ cell development during gametogenesis.

Gene References into Functions

GCNF acts as a transcriptional repressor in the regulation of OCT4 gene expression through cooperative interaction with three NR binding elements in pluripotent NCCIT cells. PMID:29057499
the genes, and up-regulated 64% in undifferentiated hES cells. In addition, GCNF also showed a regulatory gene pattern that is different from RA treatment during hES cell differentiation PMID:26769970
Findings show a role for Gcnf as a regulator of iPS cell pluripotency gene expression. It also demonstrates that reactivation of the Gcnf gene may serve as a marker to distinguish completely reprogrammed iPS cells from incompletely pluripotent cells. PMID:23495137
Our results show that cellular levels of NR6A1 are correlated with disease progression in prostate cancer. PMID:23532770
These experiments confirmed that NR6A1 works as a regulator for hypocretin transcription. PMID:21056546
RTR mRNA was expressed in the human placental choriocarcinoma cell lines BeWo, JAR, and JEG-3. PMID:11969338
characterization of a novel nuclear protein, referred to as RAP80, that interacts with the retinoid-related testis-associated receptor PMID:12080054
down-regulation of CREMtau-mediated gene expression by GCNF PMID:15456763