Map2 Antibody

Code: CSB-PA679670

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Size:

50μl100μl

US$166

Quantity:

Species Reactivity: Human,Mouse,Rat

Raised in: Rabbit

Application: ELISA,WB,IHC

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Product Details
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Target Background

Product Details

Uniprot NO.

P20357

Target Names

Map2

Alternative Names

Map2 antibody; Mtap2 antibody; Microtubule-associated protein 2 antibody; MAP-2 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide of Mouse Map2

Immunogen Species

Mus musculus (Mouse)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Tested Applications

ELISA,WB,IHC

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

Antibody FAQs

Images

The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA679670(Map2 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA679670(Map2 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
Gel: 8+10+12%SDS-PAGE, Lysate: 50 μg, Lane: Human lymphoma tissue, Primary antibody: CSB-PA679670(Map2 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 90 seconds

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Target Background

Function(From Uniprot)

The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.

Gene References into Functions

MAP2c levels in different brain regions of aging mice were positively correlated with neuropsin expression. PMID:24965600
Accumulation of intraneuronal beta-amyloid 42 peptides is associated with early changes in microtubule-associated protein 2 in neurites and synapses. PMID:23372648
results demonstrate the structural and functional determinant underlying the v-KIND-MAP2 interaction that controls dendrite arborization patterns PMID:21385318
Increased MAP2 expression in malignant melanoma cells significantly inhibits tumor cell growth and neoplasm invasiveness, and induces apoptosis and cell cycle arrest. PMID:20100193
Data show that inhibition of ZNF238 (RP58) expression in mouse GNPs decreases the expression of the neuronal differentiation markers MAP2 and NeuN and downregulates the expression of the cell cycle arrest protein p27, a regulator of GNP differentiation. PMID:20103640
Nitric oxide affects the phosphorylation state of microtubule-associated protein 2 in brain. PMID:11829530
PKA binding to MAP2 and MAP2 phosphorylation is essential for the selective development of contextual memory. PMID:12763072
Multiple brain regions exhibit potential for endogenous recovery and/or reorganization of MAP2 after injury of moderate traumatic severity. PMID:14588114
As young adults, S100B transgenic mice exhibit significantly greater MAP-2-immunoreactivity in the hippocampus, however in older adults, less MAP-2 staining is exhibited. PMID:15306236
JNK1 phosphorylation of MAP2 plays an important role in defining dendritic architecture in the brain. PMID:16000625
We also propose MAP2-deficient mice as an ideal system for identifying protein phosphatases essential for dendritic functions. PMID:16257389
MAP2 was increased in old females compared with both young and middle-age females with no significant difference in males, suggesting it may constitute a compensatory response to age-related functional decline in mice. PMID:16330151
TTLL7 is a mammalian beta-tubulin polyglutamylase required for growth of MAP2-positive neurites PMID:16901895
v-KIND mediates a signaling pathway that links Ras and MAP2 to control dendrite growth PMID:17984326
AKAP150 and Mtap2 put TREK channels at the center of a complex protein network that finely tunes channel trafficking, addressing, and regulation. PMID:18716213