LMAN1L Antibody

Code: CSB-PA862055LA01HU

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20μg50μg100μg

US$83

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Species Reactivity: Human

Raised in: Rabbit

Application: ELISA, IHC

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Target Background

Product Details

Uniprot NO.

Q9HAT1

Target Names

LMAN1L

Alternative Names

LMAN1L antibody; ERGL antibody; UNQ2784/PRO7174Protein ERGIC-53-like antibody; ERGIC53-like protein antibody; Lectin mannose-binding 1-like antibody; LMAN1-like protein antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Protein ERGIC-53-like protein (26-462AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

Antibody FAQs

Images

Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA862055LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA862055LA01HU at dilution of 1:100

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Target Background

Gene References into Functions

ERGIC-53 provides a platform that receives micro(2)L(2) subunits from the BiP-dependent checkpoint, assisting polymerization. In this process, ERp44 couples thiol-dependent assembly and quality control. PMID:17805346
Binding of ERGIC-53 to sugar is enhanced by its interaction with MCFD2, and defects in this interaction in factor V and VIII deeficient patients may be the cause for reduced secretion of factors V and VIII. PMID:18056485
The results reveal ERGIC-53 to be an intracellular transport receptor of alpha1-AT and provide direct evidence for active receptor-mediated ER export of a soluble secretory protein in higher eukaryotes PMID:18283111

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Subcellular Location

Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein.

Tissue Specificity

Highly expressed in normal and neoplastic prostate. Also expressed in cardiac atrium, salivary gland, spleen and selective cells in the CNS.

Database Links

HGNC: 6632

UNIGENE: Hs.620644

KEGG: hsa:79748

STRING: 9606.ENSP00000310431

OMIM: 609548

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