KCNK13 Antibody

Code: CSB-PA862058LA01HU
Size:
20μg
20μg50μg100μg
US$83
Quantity:
Species Reactivity: Human
Raised in: Rabbit
Application: ELISA, WB, IHC, IF
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Product Details

Uniprot NO.
Target Names
KCNK13
Alternative Names
KCNK13; Potassium channel subfamily K member 13; Tandem pore domain halothane-inhibited potassium channel 1; THIK-1
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Potassium channel subfamily K member 13 protein (292-408AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Tested Applications
ELISA, WB, IHC, IF
Recommended Dilution
ApplicationRecommended Dilution
WB1:500-1:2000
IHC1:20-1:200
IF1:50-1:200
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Datasheet & COA
Images
  • Western blot
    All lanes: KCNK13 antibody at 8µg/ml
    Lane 1: HepG2 whole cell lysate
    Lane 2: LO2 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 46 kDa
    Observed band size: 46 kDa

  • Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA862058LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human glioma using CSB-PA862058LA01HU at dilution of 1:100

  • Immunofluorescent analysis of HepG2 cells using CSB-PA862058LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Potassium channel displaying weak inward rectification in symmetrical K(+) solution.
Gene References into Functions
  1. Dysregulation of a potassium channel, THIK-1, targeted by caspase-8, accelerates cell shrinkage. PMID:27566292
  2. In cell and tissues co-expressing THIK1 and THIK2, heterodimeric channels may contribute to cell excitability. PMID:25148687
  3. expression in cell hypoxia PMID:16683720
  4. THIK-1 and THIK-2 are abundantly expressed in the proximal and distal nephron of the mammalian kidney. PMID:18209473

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Subcellular Location
Membrane; Multi-pass membrane protein.
Protein Families
Two pore domain potassium channel (TC 1.A.1.8) family
Database Links

HGNC: 6275

UNIGENE: Hs.510191

KEGG: hsa:56659

STRING: 9606.ENSP00000282146

OMIM: 607367

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