IL20RB Antibody

Code: CSB-PA125791

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Size:

100μl

US$297

Quantity:

Species Reactivity: Human,Mouse

Raised in: Rabbit

Application: ELISA,WB

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Target Background

Product Details

Uniprot NO.

Q6UXL0

Target Names

IL20RB

Alternative Names

DIRS1 antibody; Fibronectin type III domain containing 6 antibody; FNDC6 antibody; I20RB_HUMAN antibody; IL 20R beta antibody; IL 20R2 antibody; IL-20 receptor subunit beta antibody; IL-20R-beta antibody; IL-20R2 antibody; IL-20RB antibody; IL20RB antibody; Interleukin 20 receptor beta antibody; Interleukin 20 receptor beta chain precursor antibody; Interleukin 20 receptor II antibody; Interleukin-20 receptor subunit beta antibody; MGC34923 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Synthesized peptide derived from internal of Human IL20RB.

Immunogen Species

Homo sapiens (Human)

Clonality

Polyclonal

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Tested Applications

ELISA,WB

Protocols

ELISA Protocol Western Blotting(WB) Protocol

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

Antibody FAQs

Images

Western blot analysis of extracts from HeLa cells, using IL20RB antibody.

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Target Background

Function(From Uniprot)

The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor for IL20 and IL24.

Gene References into Functions

Trabecular meshwork cells express IL-20 receptors; Mutation of the T104 residue in IL-20R2 leads to a reduction in STAT3 phosphorylation as well as decreased matrix metalloproteinase activity PMID:24455976
The crystal structure of the IL-20/IL-20R1/IL-20R2 complex reveals how type I and II complexes discriminate cognate from noncognate ligands PMID:22802649
The hypotheses that genetic variations of the IL-20-RI influence susceptibility to psoriasis and single nucleotide polymorphisms (SNPs) in the IL20RA and IL20RB genes in psoriasis patients were investigated. PMID:18480827

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Subcellular Location

Membrane; Single-pass type I membrane protein.

Protein Families

Type II cytokine receptor family

Tissue Specificity

Widely expressed with highest levels in skin and testis. Highly expressed in psoriatic skin.

Database Links

HGNC: 6004

UNIGENE: Hs.61232

KEGG: hsa:53833

STRING: 9606.ENSP00000328133