IL20RA Antibody

Code: CSB-PA887035ESR1HU
Size:
20μl
20μl50μl100μl
US$83
Quantity:
Species Reactivity: Human
Raised in: Rabbit
Application: ELISA, IHC
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Product Details

Uniprot NO.
Target Names
IL20RA
Alternative Names
class II cytokine receptor ZCYTOR7 antibody; CRF2 8 antibody; CRF2-8 antibody; Cytokine receptor class II member 8 antibody; Cytokine receptor class-II member 8 antibody; Cytokine receptor family 2 member 8 antibody; I20RA_HUMAN antibody; IL 20R alpha antibody; IL 20R1 antibody; IL-20 receptor subunit alpha antibody; IL-20R-alpha antibody; IL-20R1 antibody; IL-20RA antibody; IL20 Receptor alpha antibody; IL20RA antibody; Interleukin 20 receptor alpha chain antibody; Interleukin 20 receptor, alpha antibody; interleukin-20 receptor I antibody; Interleukin-20 receptor subunit alpha antibody; ZcytoR7 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Interleukin-20 receptor subunit alpha protein (30-250AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Tested Applications
ELISA, IHC
Recommended Dilution
ApplicationRecommended Dilution
IHC1:20-1:200
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Datasheet & COA
Images
  • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA887035ESR1HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA887035ESR1HU at dilution of 1:100

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL20RA/IL10RB dimer is a receptor for IL26.
Gene References into Functions
  1. the DNA fragment containing the associated SNPs interacts through chromatin looping not only with TNFAIP3, but also with IL20RA, located 680 kb upstream. PMID:27799070
  2. IL20R1 correlated with prognosis of patients with pancreatic cancer, and mediates pancreatic cancer cell growth and migration. It may be a potential biomarker for IL24 molecular-targeted therapy. PMID:26977011
  3. crystallographic asymmetric unit contains one IL-20-IL-20R1-IL-20R2 complex, corresponding to a solvent content of approximately 54% PMID:22232181
  4. IL-20RA polymorphisms may have a role in psoriasis PMID:19926456
  5. Complete mda-7/IL-24 receptors (IL-22R1/IL-20R2 and IL-20R1/IL-20R2) are seldom expressed in liver cancer cell lines. PMID:19666410
  6. forms stable complex with interleukin-19 and interleukin-20 [IL-20R1][IL-20R2] PMID:14580208
  7. sensitivity to recombinant interleukin-26(IL-26) of various cell lines strictly correlated with the expression of IL-20 1 receptor and blocking antibodies against either IL-10 receptor 2 or IL-20 receptor 1 inhibited IL-26-dependent signal transduction PMID:15178681
  8. The hypotheses that genetic variations of the IL-20-RI influence susceptibility to psoriasis was investigated. PMID:18480827

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Subcellular Location
Membrane; Single-pass type I membrane protein.
Protein Families
Type II cytokine receptor family
Tissue Specificity
Widely expressed with highest levels in skin and testis and high levels in brain. Highly expressed in psoriatic skin.
Database Links

HGNC: 6003

UNIGENE: Hs.445868

KEGG: hsa:53832

STRING: 9606.ENSP00000314976

OMIM: 605620

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No. 269, Shendun 5th Road, Donghu Hi-Tech Development Area, Hubei Province, 430206, P.R.China
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