HS2ST1 Antibody

Code: CSB-PA010746LA01HU

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20μg50μg100μg

US$83

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Species Reactivity: Human, Rat

Raised in: Rabbit

Application: ELISA, WB, IHC

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Target Background

Product Details

Uniprot NO.

Q7LGA3

Target Names

HS2ST1

Alternative Names

2-O-sulfotransferase antibody; 2OST antibody; dJ604K5.2 antibody; FLJ11317 antibody; heparan sulfate 2 O sulfotransferase 1 antibody; Heparan sulfate 2-O-sulfotransferase 1 antibody; HS2ST_HUMAN antibody; hs2st1 antibody; KIAA0448 antibody; MGC131986 antibody

Raised in

Rabbit

Species Reactivity

Human, Rat

Immunogen

Recombinant Human Heparan sulfate 2-O-sulfotransferase 1 protein (29-229AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000
IHC	1:20-1:200

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

Antibody FAQs

Images

Western Blot
Positive WB detected in: Rat spleen tissue
All lanes: HS2ST1 antibody at 2.7µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 42, 35, 27 kDa
Observed band size: 42 kDa
Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA010746LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA010746LA01HU at dilution of 1:100

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Target Background

Function(From Uniprot)

Catalyzes the transfer of sulfate to the C2-position of selected hexuronic acid residues within the maturing heparan sulfate (HS). 2-O-sulfation within HS, particularly of iduronate residues, is essential for HS to participate in a variety of high-affinity ligand-binding interactions and signaling processes. Mediates 2-O-sulfation of both L-iduronyl and D-glucuronyl residues.

Gene References into Functions

C5-epimerase and 2-O-sulfotransferase in association generate extended domains of consecutive GlcNS-IdoA2S Sequence. PMID:25594747
analysis of differences and similarities various residues play in the biological roles of the HS-2OST and CS-2OST enzymes PMID:17227754

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Subcellular Location

Golgi apparatus membrane; Single-pass type II membrane protein.

Protein Families

Sulfotransferase 3 family

Database Links

HGNC: 5193

UNIGENE: Hs.743280

KEGG: hsa:9653

STRING: 9606.ENSP00000359581

OMIM: 604844

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