GRK7 Antibody

Code: CSB-PA002829

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Size:

50μg100μg

US$119

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Species Reactivity: Human

Raised in: Rabbit

Application: WB, IF, ELISA

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Target Background

Product Details

Uniprot NO.

Q8WTQ7

Target Names

GRK7

Alternative Names

GRK7 antibody; GPRK7 antibody; Rhodopsin kinase GRK7 antibody; EC 2.7.11.14 antibody; G protein-coupled receptor kinase 7 antibody; G protein-coupled receptor kinase GRK7 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthesized peptide derived from the Internal region of Human GRK 7.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Tested Applications

WB, IF, ELISA

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

Antibody FAQs

Images

Western Blot analysis of HeLa cells using GRK 7 Polyclonal Antibody

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Target Background

Function(From Uniprot)

Retina-specific kinase involved in the shutoff of the photoresponse and adaptation to changing light conditions via cone opsin phosphorylation, including rhodopsin (RHO).

Gene References into Functions

Defects in GRK1 or GRK7 cause patients to suffer from an inability to properly deactivate rhodopsin leading to problems with recovery and dark adaptation. PMID:22183412
Phosphorylation of GRK1 and GRK7 by PKA occurs in the dark, when cAMP levels in photoreceptor cells are elevated. PMID:15946941
synthesis of 29 of GRK1 or GRK7 partial peptides that cover the entire sequence of GRK1/GRK7, to see which interacts with recoverin. PMID:18266817

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Subcellular Location

Membrane; Lipid-anchor.

Protein Families

Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily

Tissue Specificity

Retinal cones, outer and inner segments.

Database Links

HGNC: 17031

UNIGENE: Hs.680654

KEGG: hsa:131890

STRING: 9606.ENSP00000264952