GP5 Antibody

Code: CSB-PA006196

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Size:

50μg100μg

US$119

Quantity:

Species Reactivity: Human,Mouse,Rat

Raised in: Rabbit

Application: WB, ELISA

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Product Details
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Target Background

Product Details

Uniprot NO.

P40197

Target Names

GP5

Alternative Names

GP5; Platelet glycoprotein V; GPV; Glycoprotein 5; CD antigen CD42d

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthesized peptide derived from the Internal region of Human CD42d.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Tested Applications

WB, ELISA

Protocols

Western Blotting(WB) Protocol ELISA Protocol

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

Antibody FAQs

Images

Western Blot analysis of Hela cells using CD42d Polyclonal Antibody

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function(From Uniprot)

The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis.

Gene References into Functions

Raft association and cytoskeletal linkage of the platelet GPIb-IX-V complex are interrelated, and are required for optimal receptor function by attracting signaling proteins and membrane skeletal association allows proteins to move to new locations. PMID:19874464
Both the high affinity thrombin receptor (GPIb-IX-V) and GPIIb/IIIa are implicated in expression of thrombin-induced platelet procoagulant activity. PMID:11686325
GPV is cleaved upon agonist-induced platelet activation, with ADAM17 as the major enzyme mediating this process PMID:15691827

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Subcellular Location

Membrane; Single-pass type I membrane protein.

Tissue Specificity

Platelets and megakaryocytes.

Database Links

HGNC: 4443

UNIGENE: Hs.73734

KEGG: hsa:2814

STRING: 9606.ENSP00000319286

OMIM: 173511

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