GLYAT Antibody

Code: CSB-PA009558GA01HU
Size:
100μl
100μl
US$600
Quantity:
Species Reactivity: Human,Mouse,Rat
Application: ELISA
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Product Details

Uniprot NO.
Target Names
GLYAT
Alternative Names
GLYAT antibody; ACGNAT antibody; CAT antibody; GATGlycine N-acyltransferase antibody; EC 2.3.1.13 antibody; Acyl-CoA:glycine N-acyltransferase antibody; AAc antibody; Aralkyl acyl-CoA N-acyltransferase antibody; Aralkyl acyl-CoA:amino acid N-acyltransferase antibody; Benzoyl-coenzyme A:glycine N-acyltransferase antibody; Glycine N-benzoyltransferase antibody; EC 2.3.1.71 antibody; HRP-1(CLP) antibody
Species Reactivity
Human,Mouse,Rat
Immunogen
Human GLYAT
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA
Protocols
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Datasheet & COA

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Mitochondrial acyltransferase which transfers an acyl group to the N-terminus of glycine and glutamine, although much less efficiently. Can conjugate numerous substrates to form a variety of N-acylglycines, with a preference for benzoyl-CoA over phenylacetyl-CoA as acyl donors. Thereby detoxify xenobiotics, such as benzoic acid or salicylic acid, and endogenous organic acids, such as isovaleric acid.
Gene References into Functions
  1. GLYAT exhibits mechanistic kinetic cooperativity towards its substrate glycine. PMID:28759163
  2. Data indicate that Afrikaner caucasians have a Q61L single nucleotide polymorphism (SNP) occurring at a high frequency (12%). PMID:26149650
  3. SNP variations causing amino acid substitutions in the human GLYAT gene influence the kinetic properties of the enzyme. PMID:23237781
  4. We identify GLYAT gene which appears to co-regulate bone size phenotypes (BSPs) and appendicular lean mass (ALM). PMID:23108985
  5. hGLYAT is a good candidate as a novel marker of hepatocellular carcinoma and may be a key molecule in the transition between differentiation and carcinogenesis of liver cells. PMID:22475485
  6. The aim of this work was to report a comprehensive investigation of GLYAT genetic polymorphisms in DNA samples from 55 subjects of French Caucasian origin. PMID:20925583

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Subcellular Location
Mitochondrion.
Protein Families
Glycine N-acyltransferase family
Tissue Specificity
Predominantly expressed in liver (at protein level) and kidney. Down-regulated in hepatocellular carcinoma and other liver cancers.
Database Links

HGNC: 13734

UNIGENE: Hs.145384

KEGG: hsa:10249

STRING: 9606.ENSP00000340200

OMIM: 607424

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