FRMD6 Antibody

Code: CSB-PA822270ESR2HU
Size:
20μl
20μl50μl100μl
US$83
Quantity:
Species Reactivity: Human
Raised in: Rabbit
Application: ELISA, WB, IHC
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Product Details

Uniprot NO.
Target Names
FRMD6
Alternative Names
FRMD6 antibody; C14orf31FERM domain-containing protein 6 antibody; Willin antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human FERM domain-containing protein 6 protein (413-622AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Tested Applications
ELISA, WB, IHC
Recommended Dilution
ApplicationRecommended Dilution
WB1:500-1:5000
IHC1:20-1:500
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Datasheet & COA
Images
  • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA822270ESR2HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human duodenal tissue using CSB-PA822270ESR2HU at dilution of 1:100

  • Western Blot
    Positive WB detected in: Hela whole cell lysate, HepG2 whole cell lysate
    All lanes: FRMD6 antibody at 3µg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 73, 71, 30 kDa
    Observed band size: 73 kDa

  • IHC image of CSB-PA822270ESR2HU diluted at 1:293 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Customer Reviews and Q&A

 Customer Reviews

Target Background

Gene References into Functions
  1. a novel function of FRMD6 in inhibiting human GBM growth and progression and uncover a novel mechanism by which FRMD6 exerts its anti-GBM activity. PMID:27661120
  2. Genome-wide and gene-based association implicates FRMD6 in Alzheimer disease. PMID:22190428
  3. Human homolog of Drosophila expanded, hEx, functions as a putative tumor suppressor in human cancer cell lines independently of the Hippo pathway PMID:21785462
  4. in mammalian cells willin influences Hippo signaling activity by activating the core Hippo pathway kinase cassette PMID:21666719
  5. Results describe a new FERM domain-containing protein called Willin. PMID:16137681

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Subcellular Location
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Can colocalize with actin.
Database Links

HGNC: 19839

UNIGENE: Hs.434914

KEGG: hsa:122786

STRING: 9606.ENSP00000348550

OMIM: 614555

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Address
No. 269, Shendun 5th Road, Donghu Hi-Tech Development Area, Hubei Province, 430206, P.R.China
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