EGF like domain multiple 6 antibody; EGF repeat containing protein 6 antibody; EGF-like protein 6 antibody; EGF-like-domain multiple 6 antibody; egfl6 antibody; EGFL6_HUMAN antibody; epidermal growth factor like protein 6 antibody; Epidermal growth factor-like protein 6 antibody; MAEG antibody; MAM and EGF domain containing antibody; MAM and EGF domains containing gene protein antibody; MAM and EGF domains-containing gene protein antibody; W80 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Epidermal growth factor-like protein 6 protein (301-554AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Liquid
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
May bind integrin alpha-8/beta-1 and play a role in hair follicle morphogenesis. Promotes matrix assembly.
Gene References into Functions
In conclusion, our results suggest that plasma level of EGFL6 may be useful to assess disease progression, and especially advanced T status and higher TNM stage in patients with oral squamous cell carcinoma.PMID:28539817
EGFL6 is an angiocrine and tumor cell factor that promotes tumorigenesis via SHP2-mediated signaling. EGFL6 stimulates ALDH+ ovarian cancer stem cell to migrate and undergo asymmetric division.PMID:27803106
EGFL6 was overexpressed in benign meningioma tissues and serum.PMID:23285163
results indicate that human EGFL6 is a paracrine/autocrine growth factor of adipose tissue up-regulated in obesity and potentially involved in the process of adipose tissue expansion and the development of obesityPMID:20574786
There is an absence of GNAS and EGFL6 mutations in common human cancers.PMID:18038328