Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
In the process of mRNA degradation, seems to play a role in mRNA decapping. Component of a complex containing DCP2 and DCP1A which functions in decapping of ARE-containing mRNAs. Promotes complex formation between DCP1A and DCP2. Enhances the catalytic activity of DCP2 (in vitro).
Gene References into Functions
EDC4 plays a key role in homologous recombination by stimulating end resection at double-strand breaks.PMID:29511213
The assembly of EDC4 and Dcp1a into processing bodies is critical for the translational regulation of IL-6.PMID:25970328
EDC4 is a processing body (P-body) component.PMID:24858563
The data indicates that DCP2 activation by DCP1 occurs preferentially on the EDC4 scaffold, which may serve to couple DCP2 activation by DCP1 with 5'-to-3' mRNA degradation by XRN1 in human cells.PMID:24510189
EDC4 might contribute to regulation of CoA biosynthesis in addition to its scaffold function in processing bodiesPMID:22982864