CYTH1 Antibody

Code: CSB-PA318480

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Size:

50μl100μl

US$166

Quantity:

Species Reactivity: Human,Mouse,Rat

Raised in: Rabbit

Application: ELISA,WB

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Product Details
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Target Background

Product Details

Uniprot NO.

Q15438

Target Names

CYTH1

Alternative Names

B2 1 antibody; CLM1 antibody; CTH 1 antibody; CYH1_HUMAN antibody; CYTH1 antibody; CYTIP antibody; Cytoadhesin 1 antibody; CYTOHESIN 1 antibody; Cytohesin-1 antibody; D17S811E antibody; FLJ34050 antibody; FLJ41900 antibody; Homolog of secretory protein SEC7 antibody; KIAA4240 antibody; mKIAA4240 antibody; mSec7 1 antibody; OTTHUMP00000196778 antibody; OTTHUMP00000196779 antibody; PH antibody; PH; SEC7 and coiled-coil domain containing protein 1 antibody; Pleckstrin homology Sec7 and coiled/coil domains 1 antibody; Pleckstrin homology Sec7 and coiled/coil domains protein 1 antibody; Pleckstrin homology; Sec7 and coiled coil domains 1 antibody; PSCD1 antibody; SEC7 and coiled-coil domain-containing protein 1 antibody; Sec7 antibody; SEC7 homolog A antibody; SEC7 homolog B2 1 antibody; SEC7 homolog B2-1 antibody; SEC7; yeast; homolog of antibody; Sec7a antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide of Human CYTH1

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Tested Applications

ELISA,WB

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

Antibody FAQs

Images

Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Raji cells, Primary antibody: CSB-PA318480(CYTH1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds

Customer Reviews and Q&A

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Target Background

Function(From Uniprot)

Promotes guanine-nucleotide exchange on ARF1, ARF5 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. Plays an important role in membrane trafficking, during junctional remodeling and epithelial polarization, through regulation of ARF6 activity.

Gene References into Functions

computational study suggests that although curcumin to some extent binds with Tp receptor, yet the inhibition of Arf6GDP to Arf6GTP conversion appeared to be an important mechanism by which curcumin inhibits U46619-induced increase in PLD activity in PASMCs. PMID:28780751
CYTH1 is a novel major regulator of adhesion and engraftment in human hematopoietic stem and progenitor cells through mechanisms that, at least in part, involve the activation of integrins. PMID:27899358
FRMD4A RNAi or inhibition of cytohesins strongly upregulated secretion of endogenous tau. These results suggest that FRMD4A, a genetic risk factor for late-onset Alzheimer's disease, regulates tau secretion by activating cytohesin-Arf6 signaling. PMID:27044754
cytohesin inhibition has an antiproliferative effect in gefitinib-resistant lung cancer cells PMID:22815959
findings suggest that cytohesin-1 is a key regulator of neutrophil adhesion to endothelial cells and to components of extracellular matrix, which may influence cell emigration through its dual opposing effect on beta2 and beta1 integrin activation PMID:21511340
involvement of cytohesin-1 in the regulation of the functional responses of human PMNs, linked, in part at least, to the activation of Arf6. PMID:20018626
Data show that CYTIP and cytoadhesin-1 are upregulated during dendritic cell maturation. PMID:12606567
findings reveal that mycobacteria promote their uptake through a process of "inside-out" signaling involving CD14, TLR2, PI3K, and cytohesin-1. This converts low avidity CR3 into an active receptor leading to increased bacterial internalization PMID:15778383
demonstrate an essential role of cytohesin-1/RhoA during ameboid migration in the presence of integrins PMID:19346499
Phosphorylated cytohesin-1 is able to tightly associate with the actin cytoskeleton, and is required for maximal leukocyte function antigen-1-mediated adhesion of Jurkat cells to Icam-1. PMID:11438522