CHAD Antibody

Code: CSB-PA005310GA01HU
Size:
100μl
100μl
US$600
Quantity:
Species Reactivity: Human,Mouse,Rat
Raised in: Rabbit
Application: ELISA,WB
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Product Details

Uniprot NO.
Target Names
CHAD
Alternative Names
Cartilage leucine rich protein antibody; Cartilage leucine-rich protein antibody; Chad antibody; CHAD_HUMAN antibody; Chondroadherin antibody; Chondroadherin proteoglycan antibody; SLRR4A antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human CHAD
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Datasheet & COA

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Promotes attachment of chondrocytes, fibroblasts, and osteoblasts. This binding is mediated (at least for chondrocytes and fibroblasts) by the integrin alpha(2)beta(1). May play an important role in the regulation of chondrocyte growth and proliferation.
Gene References into Functions
  1. crystal structures at ~2.2A resolution of human fibromodulin and chondroadherin. PMID:28215822
  2. number of cells adhering via their beta(1) integrin receptor to collagen type II or chondroadherin was profoundly and rapidly enhanced by the addition of the heparin-binding peptide PMID:23172228
  3. chondroadherin interaction with cells may be central for maintaining the adult chondrocyte phenotype and cartilage homeostasis. PMID:21127050
  4. Changes in CHAD abundance or structure could be associated with the pathologic changes occurring in the scoliotic IVD. PMID:19525844

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Subcellular Location
Secreted, extracellular space, extracellular matrix.
Protein Families
Small leucine-rich proteoglycan (SLRP) family, SLRP class IV subfamily
Tissue Specificity
Present in chondrocytes at all ages.
Database Links

HGNC: 1909

UNIGENE: Hs.97220

KEGG: hsa:1101

STRING: 9606.ENSP00000258969

OMIM: 602178

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