Cadherin EGF LAG seven pass G type receptor 2 flamingo Drosophila homolog antibody; Cadherin EGF LAG seven-pass G-type receptor 2 antibody; Cadherin family member 10 antibody; CDHF10 antibody; CELR2_HUMAN antibody; Celsr2 antibody; EGF like domain multiple 2 antibody; EGF-like protein 2 antibody; EGFL2 antibody; epidermal growth factor like 2 antibody; Epidermal growth factor-like protein 2 antibody; Flamingo homolog 3 antibody; Flamingo1 antibody; KIAA0279 antibody; MEGF3 antibody; Multiple EGF-like domains protein 3 antibody; Multiple epidermal growth factor-like domains 3 antibody; Multiple epidermal growth factor-like domains protein 3 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from the C-terminal region of Human CDHF10.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Tested Applications
IHC, IF, ELISA
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Receptor that may have an important role in cell/cell signaling during nervous system formation.
Gene References into Functions
Both CELSR2 and ING4 display increased cytoplasmic staining in breast cancer cells compared to benign epithelium, suggesting a possible role of both genes in the pathogenesis of human mammary neoplasia.PMID:29489009
findings suggest a rare variant in CELSR2 as causative for idiopathic scoliosis in a family with dominant segregation and further highlight common variation in CELSR2 in general susceptibility to idiopathic scoliosis in the Swedish-Danish populationPMID:29240829
we report bi-allelic mutations in CELSR2 in a Joubert patient with cortical heterotopia, microophthalmia, and growth hormone deficiency.PMID:28052552
no association was found between the SNPs of rs599839, rs464218 and rs6698843 at the CELSR2-PSRC1-SORT1 and the risk of coronary artery disease or ischemic strokePMID:26464717
CELSR2 in the cholesterol gene cluster shows a significant association with coronary artery disease and its single nucleotide polymorphism regulates plasma cholesterol levels.PMID:24674750
The novel CAD-associated locus in the vicinity of the PSRC1 and CELSR2 genes on chromosome 1 probably enhances CAD risk through an effect on plasma LDL cholesterol.PMID:18649068