CDKL3 Antibody

Code: CSB-PA150181

Rate （5.0）
Review （1）
Citation （1）

Size:

100μl

US$297

Quantity:

Species Reactivity: Human

Raised in: Rabbit

Application: ELISA,IHC

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Target Background

Product Details

Uniprot NO.

Q8IVW4

Target Names

CDKL3

Alternative Names

CDKL3 antibody; CDKL3 protein antibody; CDKL3_HUMAN antibody; Cyclin dependent kinase like 3 antibody; Cyclin-dependent kinase-like 3 antibody; Serine/threonine-protein kinase NKIAMRE antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthesized peptide derived from internal of Human CDKL3.

Immunogen Species

Homo sapiens (Human)

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Tested Applications

ELISA,IHC

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

Antibody FAQs

Images

Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue, using CDKL3 antibody.

Customer Reviews and Q&A

■ Customer Reviews

Average Rating:

5.0 - 1 reviews

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Applications : Western blot assays

Sample type: Human cells

Review: The effect of Mg2+ on the protein levels of CDKL3 in the wild-type and the mutant HeLa cells. The protein expression of CDKL3 was quantified by band intensity of the western blots with normalization to GAPDH protein. The quantified band intensity is displayed as the relative amount to the proteins in wild-type HeLa cells incubated at 0 mM Mg2+.

By Anonymous

Citations

AC-motif: a DNA motif containing adenine and cytosine repeat plays a role in gene regulation JH Hur,/,2021

Target Background

Gene References into Functions

NKIAMRE is a member of a conserved family of kinases with homology to both MAP kinases and cyclin-dependent kinases PMID:12927787
cdkl3 transfected in anchorage-independent (suspension) HeLa cells overexpressed relative to attached cells and lead to elevated proliferation and faster transition G0/G1 phases to S phase relative to controls. Same in two HEK-293 and a CHO cell lines. PMID:17945021
data suggest that the CDKL3 gene is a strong candidate for nonsyndromal autosomal dominant mild mental retardation PMID:18412109

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Subcellular Location

Cytoplasm.

Protein Families

Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily

Database Links

HGNC: 15483

UNIGENE: Hs.719926

KEGG: hsa:51265

STRING: 9606.ENSP00000265334

OMIM: 608459

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