CALCB Antibody

Code: CSB-PA004435ESR1HU

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Size:

20μl50μl100μl

US$83

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Species Reactivity: Human

Raised in: Rabbit

Application: ELISA, IHC

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Target Background

Product Details

Uniprot NO.

P10092

Target Names

CALCB

Alternative Names

Beta type CGRP antibody; Beta-CGRP antibody; Beta-type CGRP antibody; CALC2 antibody; Calcb antibody; CALCB_HUMAN antibody; Calcitonin gene related peptide 2 antibody; Calcitonin gene related peptide II antibody; Calcitonin gene-related peptide 2 antibody; Calcitonin gene-related peptide II antibody; Calcitonin related polypeptide; beta antibody; CGRP II antibody; CGRP-II antibody; CGRP2 antibody; CGRPII antibody; FLJ30166 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Calcitonin gene-related peptide 2 protein (1-127AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

Antibody FAQs

Images

Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA004435ESR1HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA004435ESR1HU at dilution of 1:100

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Target Background

Function(From Uniprot)

CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role.

Gene References into Functions

The results suggest that C12orf39, CSTA, and CALCB are novel ATF4 target genes, and that C12orf39 promoter activity is activated by ATF4 through amino acid response element. PMID:26967115
Keratinocyte-derived CGRPbeta may modulate epidermal homeostasis through autocrine/paracrine signaling and may contribute to chronic pain under pathological conditions. PMID:21641113
Calcitonin gene-related peptide stimulates proliferation of alveolar epithelial cells. PMID:19192276

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Subcellular Location

Secreted.

Protein Families

Calcitonin family

Database Links

HGNC: 1438

UNIGENE: Hs.534305

KEGG: hsa:797

STRING: 9606.ENSP00000346017

OMIM: 114160

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